Mannose-binding lectin alleles in sub-Saharan Africans and relation with susceptibility to infections

Mannose-binding lectin (MBL) plays an important role in the early stages of primary infections and during the decay of maternal antibodies in infants. Various studies have looked at the relation between serum MBL concentrations, MBL gene alterations and susceptibility to infections. We investigated...

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Veröffentlicht in:	Genes and immunity 2003-07, Vol.4 (5), p.362-367
Hauptverfasser:	Mombo, L E, Lu, C Y, Ossari, S, Bedjabaga, I, Sica, L, Krishnamoorthy, R, Lapoumeroulie, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Africa African Continental Ancestry Group Alleles Binding proteins Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research DNA Primers full-paper Fundamental and applied biological sciences. Psychology Gene Expression Genetic Predisposition to Disease Genotypes Health aspects Heterozygote HIV HIV Infections - genetics HIV-1 Human Genetics Human immunodeficiency virus Humans Immunology Infection Infections Mannose Mannose-binding lectin Mannose-Binding Lectins - genetics Microbiology Mutants Physiological aspects Polymorphism, Restriction Fragment Length Prevention Risk factors Susceptibility Tuberculosis Tuberculosis - genetics
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