Congenital abdominal aortic aneurysm: a case report
Abdominal aortic aneurysm (AAA) is distinctly uncommon in infants and children, and usually results from infection, iatrogenic trauma, vasculitis, connective tissue disorder, or tuberous sclerosis. Congenital “primary” neonatal AAA is exceedingly rare. The few reported cases of repair of congenital...
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Veröffentlicht in: | Journal of vascular surgery 2003-07, Vol.38 (1), p.190-193 |
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description | Abdominal aortic aneurysm (AAA) is distinctly uncommon in infants and children, and usually results from infection, iatrogenic trauma, vasculitis, connective tissue disorder, or tuberous sclerosis. Congenital “primary” neonatal AAA is exceedingly rare. The few reported cases of repair of congenital AAA describe use of synthetic graft material or aneurysmorrhaphy. We report the first successful treatment of a known 6 cm congenital infrarenal AAA repaired with a 5 mm cryopreserved allograft in a 4-month-old infant girl. The graft was pretreated with an antigen reduction process (SynerGraft), which preliminary studies suggest may inhibit allograft degeneration. The postoperative course was unremarkable. Lower extremity pulses and results of duplex ultrasound flow studies remained excellent at 14-month follow-up. Panel reactive antibodies against class I alloantigens remain negative. The use of an antigen-reduced allograft provides an acceptable conduit, which potentially may decrease allograft degeneration and relative graft stenosis associated with growth of the child, but requires follow-up. |
doi_str_mv | 10.1016/S0741-5214(03)00146-0 |
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Congenital “primary” neonatal AAA is exceedingly rare. The few reported cases of repair of congenital AAA describe use of synthetic graft material or aneurysmorrhaphy. We report the first successful treatment of a known 6 cm congenital infrarenal AAA repaired with a 5 mm cryopreserved allograft in a 4-month-old infant girl. The graft was pretreated with an antigen reduction process (SynerGraft), which preliminary studies suggest may inhibit allograft degeneration. The postoperative course was unremarkable. Lower extremity pulses and results of duplex ultrasound flow studies remained excellent at 14-month follow-up. Panel reactive antibodies against class I alloantigens remain negative. 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Congenital “primary” neonatal AAA is exceedingly rare. The few reported cases of repair of congenital AAA describe use of synthetic graft material or aneurysmorrhaphy. We report the first successful treatment of a known 6 cm congenital infrarenal AAA repaired with a 5 mm cryopreserved allograft in a 4-month-old infant girl. The graft was pretreated with an antigen reduction process (SynerGraft), which preliminary studies suggest may inhibit allograft degeneration. The postoperative course was unremarkable. Lower extremity pulses and results of duplex ultrasound flow studies remained excellent at 14-month follow-up. Panel reactive antibodies against class I alloantigens remain negative. The use of an antigen-reduced allograft provides an acceptable conduit, which potentially may decrease allograft degeneration and relative graft stenosis associated with growth of the child, but requires follow-up.</description><subject>Aortic Aneurysm, Abdominal - congenital</subject><subject>Aortic Aneurysm, Abdominal - diagnosis</subject><subject>Aortic Aneurysm, Abdominal - surgery</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Blood Vessel Prosthesis Implantation - methods</subject><subject>Cardiology. Vascular system</subject><subject>Cryopreservation</subject><subject>Diseases of the aorta</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Magnetic Resonance Imaging</subject><subject>Medical sciences</subject><subject>Transplantation, Homologous - immunology</subject><issn>0741-5214</issn><issn>1097-6809</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LxDAQhoMo7rr6E5ReFD1UM03apl5EFr9gwYN6DmkykUg_1qQV9t_b7i7u0dMMzDMzLw8hp0CvgUJ280ZzDnGaAL-k7IpS4FlM98gUaJHHmaDFPpn-IRNyFMLXAEEq8kMygURwDpBMCZu3zSc2rlNVpErT1q4Zu9Z3Tkeqwd6vQn0bqUirgJHH5TA5JgdWVQFPtnVGPh4f3ufP8eL16WV-v4g1Z6KLBSuVsFxYBikYRVle8lRZiqDRGgEJZzYtc8aTwhgUpVLWlClqXZSJMQVjM3Kxubv07XePoZO1CxqrasjV9kEOqynlGR_AdANq34bg0cqld7XyKwlUjrbk2pYcVUjK5NrW0MzI2fZBX9ZodltbPQNwvgVU0KqyXjXahR3HixyyYgxwt-Fw0PHj0MugHTYajfOoO2la90-UX2n1hjo</recordid><startdate>20030701</startdate><enddate>20030701</enddate><creator>Bell, Patrick</creator><creator>Mantor, Cameron</creator><creator>Jacocks, M.Alex</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20030701</creationdate><title>Congenital abdominal aortic aneurysm: a case report</title><author>Bell, Patrick ; Mantor, Cameron ; Jacocks, M.Alex</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c438t-83ba8f48f3151da037b45af0e1cefd81243f5b73429dde8baafdb5ecc9b2dd933</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Aortic Aneurysm, Abdominal - congenital</topic><topic>Aortic Aneurysm, Abdominal - diagnosis</topic><topic>Aortic Aneurysm, Abdominal - surgery</topic><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Blood Vessel Prosthesis Implantation - methods</topic><topic>Cardiology. Vascular system</topic><topic>Cryopreservation</topic><topic>Diseases of the aorta</topic><topic>Female</topic><topic>Humans</topic><topic>Infant</topic><topic>Magnetic Resonance Imaging</topic><topic>Medical sciences</topic><topic>Transplantation, Homologous - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bell, Patrick</creatorcontrib><creatorcontrib>Mantor, Cameron</creatorcontrib><creatorcontrib>Jacocks, M.Alex</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of vascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bell, Patrick</au><au>Mantor, Cameron</au><au>Jacocks, M.Alex</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Congenital abdominal aortic aneurysm: a case report</atitle><jtitle>Journal of vascular surgery</jtitle><addtitle>J Vasc Surg</addtitle><date>2003-07-01</date><risdate>2003</risdate><volume>38</volume><issue>1</issue><spage>190</spage><epage>193</epage><pages>190-193</pages><issn>0741-5214</issn><eissn>1097-6809</eissn><coden>JVSUES</coden><abstract>Abdominal aortic aneurysm (AAA) is distinctly uncommon in infants and children, and usually results from infection, iatrogenic trauma, vasculitis, connective tissue disorder, or tuberous sclerosis. Congenital “primary” neonatal AAA is exceedingly rare. The few reported cases of repair of congenital AAA describe use of synthetic graft material or aneurysmorrhaphy. We report the first successful treatment of a known 6 cm congenital infrarenal AAA repaired with a 5 mm cryopreserved allograft in a 4-month-old infant girl. The graft was pretreated with an antigen reduction process (SynerGraft), which preliminary studies suggest may inhibit allograft degeneration. The postoperative course was unremarkable. Lower extremity pulses and results of duplex ultrasound flow studies remained excellent at 14-month follow-up. Panel reactive antibodies against class I alloantigens remain negative. 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subjects | Aortic Aneurysm, Abdominal - congenital Aortic Aneurysm, Abdominal - diagnosis Aortic Aneurysm, Abdominal - surgery Biological and medical sciences Blood and lymphatic vessels Blood Vessel Prosthesis Implantation - methods Cardiology. Vascular system Cryopreservation Diseases of the aorta Female Humans Infant Magnetic Resonance Imaging Medical sciences Transplantation, Homologous - immunology |
title | Congenital abdominal aortic aneurysm: a case report |
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