Congenital abdominal aortic aneurysm: a case report

Abdominal aortic aneurysm (AAA) is distinctly uncommon in infants and children, and usually results from infection, iatrogenic trauma, vasculitis, connective tissue disorder, or tuberous sclerosis. Congenital “primary” neonatal AAA is exceedingly rare. The few reported cases of repair of congenital...

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Veröffentlicht in:Journal of vascular surgery 2003-07, Vol.38 (1), p.190-193
Hauptverfasser: Bell, Patrick, Mantor, Cameron, Jacocks, M.Alex
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container_title Journal of vascular surgery
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creator Bell, Patrick
Mantor, Cameron
Jacocks, M.Alex
description Abdominal aortic aneurysm (AAA) is distinctly uncommon in infants and children, and usually results from infection, iatrogenic trauma, vasculitis, connective tissue disorder, or tuberous sclerosis. Congenital “primary” neonatal AAA is exceedingly rare. The few reported cases of repair of congenital AAA describe use of synthetic graft material or aneurysmorrhaphy. We report the first successful treatment of a known 6 cm congenital infrarenal AAA repaired with a 5 mm cryopreserved allograft in a 4-month-old infant girl. The graft was pretreated with an antigen reduction process (SynerGraft), which preliminary studies suggest may inhibit allograft degeneration. The postoperative course was unremarkable. Lower extremity pulses and results of duplex ultrasound flow studies remained excellent at 14-month follow-up. Panel reactive antibodies against class I alloantigens remain negative. The use of an antigen-reduced allograft provides an acceptable conduit, which potentially may decrease allograft degeneration and relative graft stenosis associated with growth of the child, but requires follow-up.
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source MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects Aortic Aneurysm, Abdominal - congenital
Aortic Aneurysm, Abdominal - diagnosis
Aortic Aneurysm, Abdominal - surgery
Biological and medical sciences
Blood and lymphatic vessels
Blood Vessel Prosthesis Implantation - methods
Cardiology. Vascular system
Cryopreservation
Diseases of the aorta
Female
Humans
Infant
Magnetic Resonance Imaging
Medical sciences
Transplantation, Homologous - immunology
title Congenital abdominal aortic aneurysm: a case report
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