Trypsin inhibitor and maternal reunion increase plasma cholecystokinin in neonatal rats

Intragastric soybean trypsin inhibitor increased plasma CCK bioactivity by 87% in nondeprived, 9–12-day-old rat pups. Reunion with the dam for 1 h after overnight maternal deprivation also increased plasma CCK significantly. These results demonstrate that CCK can be released from the small intestine...

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Veröffentlicht in:Peptides (New York, N.Y. : 1980) N.Y. : 1980), 1992-09, Vol.13 (5), p.939-941
Hauptverfasser: Weller, Aron, Corp, Eric S, Tyrka, Audrey, Ritter, Robert C, Brenner, Lynne, Gibbs, James, Smith, Gerard P
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Sprache:eng
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Zusammenfassung:Intragastric soybean trypsin inhibitor increased plasma CCK bioactivity by 87% in nondeprived, 9–12-day-old rat pups. Reunion with the dam for 1 h after overnight maternal deprivation also increased plasma CCK significantly. These results demonstrate that CCK can be released from the small intestine of rats as early as postnatal day 9.
ISSN:0196-9781
1873-5169
DOI:10.1016/0196-9781(92)90052-5