Mitogenic activity of (−)epigallocatechin gallate on B-cells and investigation of its structure-function relationship

(−)Epigallocatechin gallate (EGCg), the main constituent of green tea, strongly enhanced the direct plaque-forming cell (PFC) response to sheep red blood cells (SRBC) in vitro and showed strong mitogenic activity for mouse splenic B-cells but not for splenic T-cells and thymocytes. The enhancement o...

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Veröffentlicht in:	International journal of immunopharmacology 1992-11, Vol.14 (8), p.1399-1407
Hauptverfasser:	Zhi-Qing Hu, Toda, Masako, Okubo, Sachie, Hara, Yukihiko, Shimamura, Tadakatsu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - pharmacology Animals B-Lymphocytes - drug effects B-Lymphocytes - immunology Biological and medical sciences Catechin - analogs & derivatives Catechin - pharmacology Immunomodulators Lymphocyte Activation - drug effects Male Medical sciences Mice Mice, Inbred C3H Mitogens - pharmacology Pharmacology. Drug treatments Structure-Activity Relationship T-Lymphocytes - drug effects
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