Influence of extracellular bicarbonate on the short-circuit current and intracellular free calcium of human cultured sweat duct cells

Transepithelial short-circuit current (Iscc) and intracellular free Ca2+ (Ca2+i) was studied in monolayers of cultured human sweat duct cells (CSDCs) in the presence or absence of HCO3- (and CO2) in the bathing solutions. Addition of HCO3- (and CO2) increased the control Iscc by more than 50%. The e...

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