Synaptic plasticity in the rat striatum following chronic haloperidol treatment

Administration of the dopamine (DA) antagonist haloperidol leads to the development of behavioral hypersensitivity as well as enhanced neuronal growth when striatal extracts from these animals are incubated with mesencephalic cultures. For determining if alterations in neuronal growth also occur in...

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Veröffentlicht in:	Clinical neuropharmacology 1992-12, Vol.15 (6), p.488-500
Hauptverfasser:	KERNS, J. M, SIERENS, D. K, LI CHIUNG KAO, KLAWANS, H. L, CARVEY, P. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axons - drug effects Axons - ultrastructure Biological and medical sciences Corpus Striatum - drug effects Corpus Striatum - ultrastructure Dendrites - drug effects Dendrites - ultrastructure Deoxyglucose - pharmacology Dopamine - metabolism Haloperidol - pharmacology Male Medical sciences Neuronal Plasticity - drug effects Neuropharmacology Pharmacology. Drug treatments Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology Rats Rats, Sprague-Dawley Synapses - drug effects Synapses - ultrastructure Synaptic Transmission - drug effects
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