Deletion of the Fyn-Kinase Gene Alters Behavioral Sensitivity to Ethanol

Background: An earlier study showed that deletion of the fyn‐kinase gene enhanced sensitivity to ethanol's sedative hypnotic effects and suggested that this was associated with diminished fyn‐kinase phosphorylation of NMDA receptors. The authors of that study speculated that this resulted in an...

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Veröffentlicht in:	Alcoholism, clinical and experimental research clinical and experimental research, 2003-07, Vol.27 (7), p.1033-1040
Hauptverfasser:	Boehm II, Stephen L., Peden, Laura, Chang, Rose, Harris, R. Adron, Blednov, Yuri A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Addictive behaviors Adult and adolescent clinical studies Alcoholism Animals Behavior Behavior, Addictive - enzymology Behavior, Addictive - genetics Biological and medical sciences Ethanol Ethanol - pharmacology Exploratory Behavior - drug effects Exploratory Behavior - physiology Female fyn-Kinase Gene Deletion Male Medical sciences Mice Mice, Knockout Motor Skills - drug effects Motor Skills - physiology Neoplasm Proteins Null Mutant Mouse Protein-Tyrosine Kinases - deficiency Protein-Tyrosine Kinases - genetics Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry src-Family Kinases
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