The antioxidant effect of green tea catechin ameliorates experimental liver injury

Several studies have reported green tea catechin to have both antifibrotic and anti-oxidative effects. The goal of this study was to evaluate the effect of green tea cathechin therapy in hepatic tissue injury using cholestatic rats with bile duct ligation. We performed bile duct ligation on cholesta...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2010-03, Vol.17 (3), p.197-202
Hauptverfasser:	Kobayashi, H., Tanaka, Y., Asagiri, K., Asakawa, T., Tanikawa, K., Kage, M., Yagi, Minoru
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Active oxygen Alanine Transaminase - blood Aldehydes - metabolism Analysis Animals Anti-oxidant therapy Antioxidants Antioxidants - pharmacology Antioxidants - therapeutic use Aspartate Aminotransferases - blood Bile acids Camellia sinensis - chemistry Catechin Catechin - pharmacology Catechin - therapeutic use Cholestasis - complications Cholestasis - drug therapy Cholestasis - metabolism Deoxyguanosine - analogs & derivatives Deoxyguanosine - metabolism Disease Models, Animal Green tea Health aspects Hepatic Stellate Cells - drug effects Hepatic Stellate Cells - metabolism Hepatitis C Immunohistochemistry Isoflavones Liver - drug effects Liver - metabolism Liver - pathology Liver cirrhosis Liver Cirrhosis - drug therapy Liver Cirrhosis - etiology Liver Cirrhosis - metabolism Liver fibrosis Male Monoclonal antibodies Oxidative Stress - drug effects Physiological aspects Phytotherapy Plant Extracts - pharmacology Plant Extracts - therapeutic use Rats Rats, Wistar RNA, Messenger - metabolism Tissue Inhibitor of Metalloproteinase-1 - genetics Tissue Inhibitor of Metalloproteinase-1 - metabolism Transcription Factor AP-1 - genetics Transcription Factor AP-1 - metabolism Transforming Growth Factor beta1 - metabolism Transplantation of organs, tissues, etc
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