Monoamine levels in rat striatum after acute intraperitoneal injection of strictosidinic acid isolated from Psychotria myriantha Mull. Arg. (Rubiaceae)

Strictosidinic acid 10 mg/kg, isolated from Psychotria myriantha leaves, were administered intraperitoneally to Wistar male rats (n=5-6). After 60 minutes, striatum was dissected, homogenized and injected onto HPLC-ED chromatographic system. It was observed a 28.7% reduction in the 5-HT levels follo...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2010-03, Vol.17 (3), p.289-291
Hauptverfasser:	Farias, F.M., Passos, C.S., Arbo, M.D., Zuanazzi, J.A.S., Steffen, V.M., Henriques, A.T.
Format:	Artikel
Sprache:	eng
Schlagworte:	3,4-Dihydroxyphenylacetic Acid - metabolism Alkaloids Animals Carbolines - isolation & purification Carbolines - pharmacology Corpus Striatum - drug effects Corpus Striatum - metabolism Dopamine - metabolism Glycosides - isolation & purification Glycosides - pharmacology Health aspects Homovanillic Acid - metabolism Injections, Intraperitoneal Male Metabolites Migraine Monoamine levels Neurotransmitter Agents - administration & dosage Neurotransmitter Agents - isolation & purification Neurotransmitter Agents - pharmacology Phenylacetates - metabolism Plant Extracts - administration & dosage Plant Extracts - chemistry Plant Extracts - pharmacology Plant Leaves Psychotria myriantha Rats Rats, Wistar Rubiaceae - chemistry Serotonin - analogs & derivatives Serotonin - metabolism Striatum Strictosidinic acid
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