Cytokine genes are associated with tuberculin skin test response in a native Brazilian population

Summary Tuberculosis was a major cause of population decline among Brazilian indigenous peoples and remains a leading cause of morbidity and mortality among them. Despite high BCG coverage, results of Tuberculin Skin Test (TST) reactivity have shown high rates of anergy in Amazonian Indians. Given t...

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Veröffentlicht in:	Tuberculosis (Edinburgh, Scotland) Scotland), 2010-01, Vol.90 (1), p.44-49
Hauptverfasser:	Zembrzuski, Verônica M, Basta, Paulo C, Callegari-Jacques, Sidia M, Santos, Ricardo V, Coimbra, Carlos E.A, Salzano, Francisco M, Hutz, Mara H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Brazil - epidemiology Brazilian Indians Child Child, Preschool Clonal Anergy - genetics Cytokines - genetics Cytokines - immunology Female Genetic Predisposition to Disease Genetic susceptibility Humans Immune response genes Indians, South American Infant Infectious Disease Interferon-gamma - genetics Male Middle Aged Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - immunology Polymorphism, Single Nucleotide Polymorphisms Prevalence Pulmonary/Respiratory T-Lymphocytes, Helper-Inducer - immunology Tuberculin skin test reactivity Tuberculin Test Tuberculosis - epidemiology Tuberculosis - genetics Tuberculosis - immunology Young Adult
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