Kinetics of bilirubin oxidase and modeling of an immobilized bilirubin oxidase reactor for bilirubin detoxification

The unbound bilirubin concentration and the enzymatic rate of bilirubin degradation by bilirubin oxidase in bilirubin‐serum albumin solutions have been investigated experimentally and theoretically. A stoichiometric bilirubin‐serum albumin binding analysis shows that the unbound bilirubin concentrat...

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Veröffentlicht in:	Biotechnology and bioengineering 1988-04, Vol.31 (6), p.536-546
Hauptverfasser:	Million, Claudy J. P., Klibanov, Alexander M., Langer, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Biological and medical sciences Biotechnology Enzymes and enzyme inhibitors Fundamental and applied biological sciences. Psychology Health. Pharmaceutical industry Industrial applications and implications. Economical aspects Medical applications of immobilized enzymes Oxidoreductases
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