Right ventricular beneficial effects of intracoronary SERCA2a gene transfer in an experimental model of heart failure

SERCA2a gene transfer ameliorates heart failure pathologic processes in left ventricular myocardium. We sought to assess the simultaneous molecular changes that occur in the right ventricle. Sprague-Dawley rats underwent aortic banding and were followed by echocardiography for development of heart f...

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Veröffentlicht in:	Folia biologica 2010, Vol.56 (1), p.1-8
Hauptverfasser:	Molina, E J, Gupta, D, Palma, J, Gaughan, J P, Macha, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - genetics Adenoviridae - metabolism Animals Biomarkers - metabolism Gene Transfer Techniques Heart Failure - pathology Heart Failure - physiopathology Heart Failure - therapy Heart Ventricles - pathology Heart Ventricles - physiopathology Humans Male Random Allocation Rats Rats, Sprague-Dawley Sarcoplasmic Reticulum Calcium-Transporting ATPases - genetics Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism Transgenes Virus Replication
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