High-fat Diet Followed by Fasting Disrupts Circadian Expression of Adiponectin Signaling Pathway in Muscle and Adipose Tissue

The circadian clock controls energy homeostasis by regulating circadian expression of proteins involved in metabolism. Disruption of circadian rhythms leads to obesity and metabolic disorders. Little is known regarding the control of the biological clock over adiponectin signaling pathway in adipose...

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Veröffentlicht in:	Obesity (Silver Spring, Md.) Md.), 2010-02, Vol.18 (2), p.230-238
Hauptverfasser:	Barnea, Maayan, Madar, Zecharia, Froy, Oren
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetyl-CoA Carboxylase - genetics Adenosine Adipocytes adiponectin Adiponectin - metabolism adiponectin receptors adipose tissue Adipose Tissue - metabolism AMP-Activated Protein Kinases - genetics Animals biochemical pathways Biological clocks blood glucose Blood Glucose - metabolism Body fat Circadian rhythm Circadian Rhythm - genetics Circadian Rhythm Signaling Peptides and Proteins - genetics Diet Dietary Fats - administration & dosage Dietary Fats - metabolism energy fasting Fasting - metabolism Fatty acids gene expression Gene Expression Regulation genes Glucose high fat diet homeostasis Humidity insulin Insulin - blood Insulin resistance Kinases Laboratories Lipids Male messenger RNA metabolic diseases Metabolism Mice Mice, Inbred C57BL Muscle, Skeletal - metabolism muscles Obesity Oxidation PPAR alpha - genetics PPAR gamma - genetics Proteins Receptors, Adiponectin - genetics RNA, Messenger - metabolism signal transduction Signal Transduction - genetics
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