Myeloid Expression of Cytochrome P450 4F3 Is Determined by a Lineage-specific Alternative Promoter

The cytochrome P450 4F3 ( CYP4F3 ) gene encodes two functionally distinct enzymes that differ only by the selection of exon 4 (CYP4F3A) or exon 3 (CYP4F3B). CYP4F3A inactivates leukotriene B 4 , a reaction that has significance for controlling inflammation. CYP4F3B converts arachidonic acid to 20-hy...

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Veröffentlicht in:	The Journal of biological chemistry 2003-07, Vol.278 (27), p.25133-25142
Hauptverfasser:	Christmas, Peter, Carlesso, Nadia, Shang, Haibo, Cheng, Shing-Ming, Weber, Brittany M, Preffer, Frederic I, Scadden, David T, Soberman, Roy J
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Bone Marrow Cells - cytology Bone Marrow Cells - enzymology Cell Lineage - genetics Cells, Cultured Cytochrome P-450 Enzyme System - biosynthesis Cytochrome P-450 Enzyme System - genetics Cytochrome P450 Family 4 Flow Cytometry Gene Expression Regulation, Enzymologic Humans Isoenzymes - biosynthesis Isoenzymes - genetics Molecular Sequence Data Promoter Regions, Genetic - genetics
Online-Zugang:	Volltext
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