Chronic treatment with agonists of beta(2)-adrenergic receptors in neuropathic pain

Expression of beta(2)-adrenoceptors (beta(2)-ARs) within the nociceptive system suggested their potential implication in nociception and pain. Recently, we demonstrated that these receptors are essential for neuropathic pain treatment by antidepressant drugs. The aim of the present study was to inve...

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Veröffentlicht in:	Experimental neurology 2010-01, Vol.221 (1), p.115-121
Hauptverfasser:	Yalcin, Ipek, Tessier, Luc-Henri, Petit-Demoulière, Nathalie, Waltisperger, Elisabeth, Hein, Lutz, Freund-Mercier, Marie-José, Barrot, Michel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-2 Receptor Agonists Adrenergic beta-Agonists - pharmacology Adrenergic beta-Agonists - therapeutic use Adrenergic beta-Antagonists - pharmacology Animals Disease Models, Animal Dose-Response Relationship, Drug Drug Administration Schedule Drug Interactions Functional Laterality Male Mice Mice, Inbred C57BL Mice, Knockout Naltrexone - analogs & derivatives Naltrexone - pharmacology Narcotic Antagonists - pharmacology Pain Measurement - methods Pain Threshold - drug effects Pain Threshold - physiology Propanolamines - pharmacology Receptors, Adrenergic, beta-2 - deficiency Sciatica - drug therapy Sciatica - physiopathology Time Factors
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