Hepatic resection for metastatic renal tumors: is it worthwhile?

Liver metastases of malignant renal tumors are regarded as having an ominous prognosis because they are infrequently amenable to radical surgery and respond poorly to chemotherapy. Little is known of the outcome of isolated metastases to the liver for which resection is potentially curative. Data on...

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Veröffentlicht in:Annals of surgical oncology 2003-07, Vol.10 (6), p.705-710
Hauptverfasser: Alves, A, Adam, R, Majno, P, Delvart, V, Azoulay, D, Castaing, D, Bismuth, H
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Sprache:eng
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Zusammenfassung:Liver metastases of malignant renal tumors are regarded as having an ominous prognosis because they are infrequently amenable to radical surgery and respond poorly to chemotherapy. Little is known of the outcome of isolated metastases to the liver for which resection is potentially curative. Data on 14 patients with liver metastases from renal tumors who underwent a liver resection in a single center between 1982 and 2001 were analyzed retrospectively. There was no operative or postoperative mortality. The median survival was 26 months, with a survival rate of 69% at 1 year and 26% at 3 years. The curative pattern of hepatectomy (2-year survival, 69% vs. 0%; P =.001), an interval between the nephrectomy and the diagnosis of liver metastases in excess of 24 months (2-year survival, 71% vs. 25%; P =.05), tumor size
ISSN:1068-9265
1534-4681
DOI:10.1245/aso.2003.07.024