Growth-inhibiting and Apoptosis-inducing Effects of Tanshinone Ⅱ A on Human Gastric Carcinoma Cells

To explore the effects of Tanshinone Ⅱ A on the proliferation, apoptosis and gene expression of p53 and bcl-2 in human gastric carcinoma MKN-45 cells. Cell count and MTT assay were used to study the proliferation-inhibiting effect of Tanshinone Ⅱ A on MKN-45 cells. The effect of Tanshinone Ⅱ A on th...

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Veröffentlicht in:	Journal of Huazhong University of Science and Technology. Medical sciences 2007-12, Vol.27 (6), p.706-709
1. Verfasser:	董晓荣董继华彭纲侯晓华伍钢
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Phytogenic - pharmacology Apoptosis - drug effects Cell Line, Tumor Cell Proliferation - drug effects Diterpenes, Abietane Drugs, Chinese Herbal - pharmacology Gene Expression Regulation, Neoplastic Humans Phenanthrenes - pharmacology Proto-Oncogene Proteins c-bcl-2 - metabolism Stomach Neoplasms - pathology Tumor Suppressor Protein p53 - metabolism 生长抑制癌细胞细胞凋亡细胞循环
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