Donor-specific antigen transfusion-mediated skin-graft tolerance results from the peripheral deletion of donor-reactive CD8+ T cells

The mechanism of donor-specific transfusion (DST)-induced long-term skin-graft survival is examined in 2CF1 (2C x dm2) transgenic and B6F1 (C57BL/6 x dm2) nontransgenic mice in which CB6F1 (Balb/c x B6) DST and donor skin grafts differ from 2CF1 or B6F1 recipients only at major histocompatibility co...

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Veröffentlicht in:	Transplantation 2003-06, Vol.75 (12), p.2119-2127
Hauptverfasser:	MARGENTHALER, Julie A, KATAOKA, Masaaki, FLYE, M. Wayne
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive Transfer Animals Biological and medical sciences CD4 Antigens - genetics CD4 Antigens - immunology CD8 antigen CD8 Antigens - genetics CD8 Antigens - immunology Combined surgery. Multiple transplantations Graft Survival - immunology Isoantigens - therapeutic use Lymphocyte Depletion Medical sciences Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Inbred Strains Mice, Transgenic Skin Transplantation - immunology Spleen - immunology Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Online-Zugang:	Volltext
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