Mitochondria and reperfusion injury. The role of permeability transition

The viability of the ischemic myocardium is jeopardized by alterations, such as ATP decrease and elevation in intracellular [Ca(2+)], that are related to derangements in mitochondrial function. Besides these established notions, the elucidation of the apoptotic cascade and the availability of novel...

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Veröffentlicht in:	Basic research in cardiology 2003-07, Vol.98 (4), p.235-241
Hauptverfasser:	Di Lisa, Fabio, Canton, Marcella, Menabò, Roberta, Dodoni, Giuliano, Bernardi, Paolo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Cell Membrane Permeability - physiology Humans Mitochondria - metabolism Myocardial Reperfusion Injury - metabolism Myocardial Reperfusion Injury - physiopathology
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