Polycation gene delivery systems: escape from endosomes to cytosol

Clinical success of gene therapy based on oligonucleotides (ODNs), ribozymes, RNA and DNA will be greatly dependent on the availability of effective delivery systems. Polycations have gained increasing attention as a non‐viral gene delivery vector in the past decades. Significant progress has been m...

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Veröffentlicht in:	Journal of pharmacy and pharmacology 2003-06, Vol.55 (6), p.721-734
Hauptverfasser:	Cho, Yong Woo, Kim, Jong-Duk, Park, Kinam
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cytosol DNA-Binding Proteins - chemistry Drug Delivery Systems - methods Endosomes Genetic Therapy - methods Humans Medical sciences Peptides - chemistry Polyamines - chemistry Structure-Activity Relationship
Online-Zugang:	Volltext
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