Human papillomavirus type 16 found in primary transitional cell carcinoma of the Bartholin's gland and in a lymph node metastasis
We report a case of primary transitional cell carcinoma of the Bartholin's gland and its lymph node metastasis that contained HPV 16 sequences by polymerase chain reaction. The physical state of HPV 16 DNA in the primary cancer was investigated by Southern blot analysis which showed the presenc...
Gespeichert in:
Veröffentlicht in: | Gynecologic oncology 1992, Vol.47 (2), p.263-266 |
---|---|
Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 266 |
---|---|
container_issue | 2 |
container_start_page | 263 |
container_title | Gynecologic oncology |
container_volume | 47 |
creator | Scinicariello, Franco Rady, Peter Hannigan, Edward Dinh, Tung V. Tyring, Stephen K. |
description | We report a case of primary transitional cell carcinoma of the Bartholin's gland and its lymph node metastasis that contained HPV 16 sequences by polymerase chain reaction. The physical state of HPV 16 DNA in the primary cancer was investigated by Southern blot analysis which showed the presence of the episomal form of viral DNA. Our findings of HPV 16 DNA in the transitional cell carcinoma of the Bartholin's gland and its metastasis would indicate that both tumors arose from a single clonal event, thus providing evidence that the HPV 16 may have an oncogenic potential in this rare malignancy even in the episomal state. |
doi_str_mv | 10.1016/0090-8258(92)90118-3 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_73422822</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0090825892901183</els_id><sourcerecordid>73422822</sourcerecordid><originalsourceid>FETCH-LOGICAL-c367t-c2c6573a15558f13dafb06ef15cd00fe5f695fb383443dfb093d0359a94bb50a3</originalsourceid><addsrcrecordid>eNp9kEtrFTEYhkNR6rH2H7SQlZfFaC6TOZONoKW1QqEbXYdvcvFEZpIxyRTO0n_enM6h7oSQLN5LeB-ELij5SAntPhEiSdMz0b-X7IMklPYNP0EbSqRoul7IF2jzbHmFXuf8mxDCCWWn6JRy3kreb9Df22WCgGeY_TjGCR58WjIu-9li2mEXl2Cwr3ryE6Q9LglC9sXHACPWdqwXJO1DTeLocNlZ_BVS2cXRh3cZ_xqh5mHtADzup3mHQzQWT7ZArsfnN-ilgzHb8-N7hn7eXP-4um3u7r99v_py12jebUujme7ElgMVQvSOcgNuIJ11VGhDiLPCdVK4gfe8bbmpmuSGcCFBtsMgCPAz9HbtnVP8s9hc1OTzYQIEG5estrxlrGesGtvVqFPMOVmnjusVJepAXh2wqgNWJZl6Iq94jV0e-5dhsuZfaEVd9c-rbuvIB2-TytrboK3xyeqiTPT__-ARNEuUFQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>73422822</pqid></control><display><type>article</type><title>Human papillomavirus type 16 found in primary transitional cell carcinoma of the Bartholin's gland and in a lymph node metastasis</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Scinicariello, Franco ; Rady, Peter ; Hannigan, Edward ; Dinh, Tung V. ; Tyring, Stephen K.</creator><creatorcontrib>Scinicariello, Franco ; Rady, Peter ; Hannigan, Edward ; Dinh, Tung V. ; Tyring, Stephen K.</creatorcontrib><description>We report a case of primary transitional cell carcinoma of the Bartholin's gland and its lymph node metastasis that contained HPV 16 sequences by polymerase chain reaction. The physical state of HPV 16 DNA in the primary cancer was investigated by Southern blot analysis which showed the presence of the episomal form of viral DNA. Our findings of HPV 16 DNA in the transitional cell carcinoma of the Bartholin's gland and its metastasis would indicate that both tumors arose from a single clonal event, thus providing evidence that the HPV 16 may have an oncogenic potential in this rare malignancy even in the episomal state.</description><identifier>ISSN: 0090-8258</identifier><identifier>EISSN: 1095-6859</identifier><identifier>DOI: 10.1016/0090-8258(92)90118-3</identifier><identifier>PMID: 1334938</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Bartholin's Glands - microbiology ; Blotting, Southern ; Carcinoma, Transitional Cell - microbiology ; Carcinoma, Transitional Cell - secondary ; Female ; Humans ; Lymphatic Metastasis ; Papillomaviridae - isolation & purification ; Polymerase Chain Reaction ; Tumor Virus Infections - diagnosis ; Vulvar Neoplasms - microbiology</subject><ispartof>Gynecologic oncology, 1992, Vol.47 (2), p.263-266</ispartof><rights>1992</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c367t-c2c6573a15558f13dafb06ef15cd00fe5f695fb383443dfb093d0359a94bb50a3</citedby><cites>FETCH-LOGICAL-c367t-c2c6573a15558f13dafb06ef15cd00fe5f695fb383443dfb093d0359a94bb50a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0090-8258(92)90118-3$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,4024,27923,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1334938$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Scinicariello, Franco</creatorcontrib><creatorcontrib>Rady, Peter</creatorcontrib><creatorcontrib>Hannigan, Edward</creatorcontrib><creatorcontrib>Dinh, Tung V.</creatorcontrib><creatorcontrib>Tyring, Stephen K.</creatorcontrib><title>Human papillomavirus type 16 found in primary transitional cell carcinoma of the Bartholin's gland and in a lymph node metastasis</title><title>Gynecologic oncology</title><addtitle>Gynecol Oncol</addtitle><description>We report a case of primary transitional cell carcinoma of the Bartholin's gland and its lymph node metastasis that contained HPV 16 sequences by polymerase chain reaction. The physical state of HPV 16 DNA in the primary cancer was investigated by Southern blot analysis which showed the presence of the episomal form of viral DNA. Our findings of HPV 16 DNA in the transitional cell carcinoma of the Bartholin's gland and its metastasis would indicate that both tumors arose from a single clonal event, thus providing evidence that the HPV 16 may have an oncogenic potential in this rare malignancy even in the episomal state.</description><subject>Adult</subject><subject>Bartholin's Glands - microbiology</subject><subject>Blotting, Southern</subject><subject>Carcinoma, Transitional Cell - microbiology</subject><subject>Carcinoma, Transitional Cell - secondary</subject><subject>Female</subject><subject>Humans</subject><subject>Lymphatic Metastasis</subject><subject>Papillomaviridae - isolation & purification</subject><subject>Polymerase Chain Reaction</subject><subject>Tumor Virus Infections - diagnosis</subject><subject>Vulvar Neoplasms - microbiology</subject><issn>0090-8258</issn><issn>1095-6859</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1992</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtrFTEYhkNR6rH2H7SQlZfFaC6TOZONoKW1QqEbXYdvcvFEZpIxyRTO0n_enM6h7oSQLN5LeB-ELij5SAntPhEiSdMz0b-X7IMklPYNP0EbSqRoul7IF2jzbHmFXuf8mxDCCWWn6JRy3kreb9Df22WCgGeY_TjGCR58WjIu-9li2mEXl2Cwr3ryE6Q9LglC9sXHACPWdqwXJO1DTeLocNlZ_BVS2cXRh3cZ_xqh5mHtADzup3mHQzQWT7ZArsfnN-ilgzHb8-N7hn7eXP-4um3u7r99v_py12jebUujme7ElgMVQvSOcgNuIJ11VGhDiLPCdVK4gfe8bbmpmuSGcCFBtsMgCPAz9HbtnVP8s9hc1OTzYQIEG5estrxlrGesGtvVqFPMOVmnjusVJepAXh2wqgNWJZl6Iq94jV0e-5dhsuZfaEVd9c-rbuvIB2-TytrboK3xyeqiTPT__-ARNEuUFQ</recordid><startdate>1992</startdate><enddate>1992</enddate><creator>Scinicariello, Franco</creator><creator>Rady, Peter</creator><creator>Hannigan, Edward</creator><creator>Dinh, Tung V.</creator><creator>Tyring, Stephen K.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1992</creationdate><title>Human papillomavirus type 16 found in primary transitional cell carcinoma of the Bartholin's gland and in a lymph node metastasis</title><author>Scinicariello, Franco ; Rady, Peter ; Hannigan, Edward ; Dinh, Tung V. ; Tyring, Stephen K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c367t-c2c6573a15558f13dafb06ef15cd00fe5f695fb383443dfb093d0359a94bb50a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1992</creationdate><topic>Adult</topic><topic>Bartholin's Glands - microbiology</topic><topic>Blotting, Southern</topic><topic>Carcinoma, Transitional Cell - microbiology</topic><topic>Carcinoma, Transitional Cell - secondary</topic><topic>Female</topic><topic>Humans</topic><topic>Lymphatic Metastasis</topic><topic>Papillomaviridae - isolation & purification</topic><topic>Polymerase Chain Reaction</topic><topic>Tumor Virus Infections - diagnosis</topic><topic>Vulvar Neoplasms - microbiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Scinicariello, Franco</creatorcontrib><creatorcontrib>Rady, Peter</creatorcontrib><creatorcontrib>Hannigan, Edward</creatorcontrib><creatorcontrib>Dinh, Tung V.</creatorcontrib><creatorcontrib>Tyring, Stephen K.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Gynecologic oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Scinicariello, Franco</au><au>Rady, Peter</au><au>Hannigan, Edward</au><au>Dinh, Tung V.</au><au>Tyring, Stephen K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Human papillomavirus type 16 found in primary transitional cell carcinoma of the Bartholin's gland and in a lymph node metastasis</atitle><jtitle>Gynecologic oncology</jtitle><addtitle>Gynecol Oncol</addtitle><date>1992</date><risdate>1992</risdate><volume>47</volume><issue>2</issue><spage>263</spage><epage>266</epage><pages>263-266</pages><issn>0090-8258</issn><eissn>1095-6859</eissn><abstract>We report a case of primary transitional cell carcinoma of the Bartholin's gland and its lymph node metastasis that contained HPV 16 sequences by polymerase chain reaction. The physical state of HPV 16 DNA in the primary cancer was investigated by Southern blot analysis which showed the presence of the episomal form of viral DNA. Our findings of HPV 16 DNA in the transitional cell carcinoma of the Bartholin's gland and its metastasis would indicate that both tumors arose from a single clonal event, thus providing evidence that the HPV 16 may have an oncogenic potential in this rare malignancy even in the episomal state.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>1334938</pmid><doi>10.1016/0090-8258(92)90118-3</doi><tpages>4</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0090-8258 |
ispartof | Gynecologic oncology, 1992, Vol.47 (2), p.263-266 |
issn | 0090-8258 1095-6859 |
language | eng |
recordid | cdi_proquest_miscellaneous_73422822 |
source | MEDLINE; Access via ScienceDirect (Elsevier) |
subjects | Adult Bartholin's Glands - microbiology Blotting, Southern Carcinoma, Transitional Cell - microbiology Carcinoma, Transitional Cell - secondary Female Humans Lymphatic Metastasis Papillomaviridae - isolation & purification Polymerase Chain Reaction Tumor Virus Infections - diagnosis Vulvar Neoplasms - microbiology |
title | Human papillomavirus type 16 found in primary transitional cell carcinoma of the Bartholin's gland and in a lymph node metastasis |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T12%3A27%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Human%20papillomavirus%20type%2016%20found%20in%20primary%20transitional%20cell%20carcinoma%20of%20the%20Bartholin's%20gland%20and%20in%20a%20lymph%20node%20metastasis&rft.jtitle=Gynecologic%20oncology&rft.au=Scinicariello,%20Franco&rft.date=1992&rft.volume=47&rft.issue=2&rft.spage=263&rft.epage=266&rft.pages=263-266&rft.issn=0090-8258&rft.eissn=1095-6859&rft_id=info:doi/10.1016/0090-8258(92)90118-3&rft_dat=%3Cproquest_cross%3E73422822%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=73422822&rft_id=info:pmid/1334938&rft_els_id=0090825892901183&rfr_iscdi=true |