Effect of prostaglandin E2 on intercellular adhesion molecule-1 and B7 expression in mixed lymphocyte reaction

The elevation of plasma interleukin (IL)-18 levels and the expression of intercellular adhesion molecule (ICAM)-1 and B7 on monocytes are involved in acute rejection. Prostaglandin (PG) E2 suppresses the rejection in animal transplantation models; however, little is known about its action mechanism....

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Veröffentlicht in:	Transplantation 2003-06, Vol.75 (12), p.2100-2105
Hauptverfasser:	MORICHIKA, Toshihiko, TAKAHASHI, Hideo K, TANAKA, Noriaki, IWAGAKI, Hiromi, YAGI, Takahito, SAITO, Shinnya, KUBO, Shinichiro, YOSHINO, Tadashi, AKAGI, Tadaatsu, MORI, Shuji, NISHIBORI, Masahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	B7 antigen B7-1 Antigen - genetics Biological and medical sciences Combined surgery. Multiple transplantations Dinoprostone - pharmacology Enzyme-Linked Immunosorbent Assay Humans intercellular adhesion molecule 1 Intercellular Adhesion Molecule-1 - genetics Interleukin-18 - pharmacology Lymphocyte Culture Test, Mixed Medical sciences Monocytes - drug effects Monocytes - immunology Recombinant Proteins - pharmacology Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
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