Methylene blue: the drug of choice for catecholamine-refractory vasoplegia after cardiopulmonary bypass

Vasoplegia is a frequent complication after cardiopulmonary bypass that often requires the application of norepinephrine. In a number of cases, however, vasoplegia is refractory to norepinephrine. The guanylate cyclase inhibitor methylene blue could be an attractive treatment alternative in such cas...

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