Pharmacokinetics and safety of single and multiple doses of Asacol tablets in Japanese healthy volunteers

Introduction The pharmacokinetics and safety of Asacol ® (Tillotts Pharma AG, Ziefen, Switzerland), which has been used worldwide to treat ulcerative colitis and Crohn’s disease, were studied in Japanese healthy male volunteers. Methods Drug plasma concentrations and urinary and fecal excretions aft...

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Veröffentlicht in:	Advances in therapy 2009-08, Vol.26 (8), p.749-761
Hauptverfasser:	Ito, Hiroaki, Furuta, Shigeru, Sasaki, Hidetaka, Yoshida, Toyomitsu, Takano, Yuichi, Hibi, Toshifumi
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Anti-Inflammatory Agents, Non-Steroidal - metabolism Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics Area Under Curve Cardiology Colitis, Ulcerative - drug therapy Crohn Disease - drug therapy Double-Blind Method Drug Administration Schedule Drug Monitoring Endocrinology Food-Drug Interactions Health technology assessment Humans Internal Medicine Japan Male Medicine Medicine & Public Health Mesalamine - administration & dosage Mesalamine - metabolism Mesalamine - pharmacokinetics Metabolic Clearance Rate Middle Aged Oncology Original Research Pharmacology/Toxicology Rheumatology Safety Tablets Time Factors
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