Kinetic Resolution of the Racemic 2-Hydroxyalkanoates Using the Enantioselective Mixed-Anhydride Method with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst

A variety of optically active 2‐hydroxyalkanoates and the corresponding 2‐acyloxyalkanoates are produced by the kinetic resolution of racemic 2‐hydroxyalkanoates by using achiral 2,2‐diarylacetic acid with hindered carboxylic anhydrides as the coupling reagents. The combined use of diphenylacetic ac...

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