HMGA2: A Potential Biomarker Complement to P53 for Detection of Early-stage High-grade Papillary Serous Carcinoma in Fallopian Tubes

Before high-grade papillary serous carcinoma (HG-PSC) becomes invasive, it is believed to be a poorly defined short-lived precursor lesion. A recent characterization of serous tubal intraepithelial carcinoma (STIC) and of the p53 signature suggested that HG-PSC may follow a stepwise progression on c...

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Veröffentlicht in:	The American journal of surgical pathology 2010, Vol.34 (1), p.18-26
Hauptverfasser:	WEI, Jian-Jun, JINGJING WU, CHUNYAN LUAN, YELDANDI, Anjana, LEE, Peng, KEH, Pacita, JINSONG LIU
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Biomarkers, Tumor - analysis Cystadenocarcinoma, Serous - metabolism Cystadenocarcinoma, Serous - pathology Fallopian Tube Neoplasms - metabolism Fallopian Tube Neoplasms - pathology Female HMGA2 Protein - biosynthesis Humans Immunohistochemistry Investigative techniques, diagnostic techniques (general aspects) Medical sciences Middle Aged Neoplasm Staging Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Precancerous Conditions - metabolism Precancerous Conditions - pathology Tumor Suppressor Protein p53 - biosynthesis
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