Low grade malignant peripheral nerve sheath tumor with smooth muscle differentiation

Malignant peripheral nerve sheath tumors are usually Schwann cell derived. Differentiation along mesenchymal lines is uncommon. Herein we present an example with smooth muscle differentiation occurring in the left distal forearm of a 62-year-old male with neurofibromatosis type I. Incisional biopsy...

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Veröffentlicht in:	Acta neuropathologica 2007-06, Vol.113 (6), p.705-709
Hauptverfasser:	Rodriguez, Fausto J, Scheithauer, Bernd W, Abell-Aleff, Patrice C, Elamin, Elshami, Erlandson, Robert A
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Methylisoborneol Actin Biopsy Bone Neoplasms - secondary CD57 antigen Cell differentiation Cell Differentiation - physiology Desmin Electron microscopy Fatal Outcome Forearm Forearm - pathology Genetic disorders Glial fibrillary acidic protein Humans Immunohistochemistry Low Back Pain - etiology Male Membrane proteins Mesenchyme Microfilaments Microscopy, Electron Middle Aged Muscle, Smooth - pathology Myogenin Nerve Sheath Neoplasms - pathology Neurofibromatosis Neurofibromatosis 1 - complications Neurofibromatosis 1 - pathology Neurofilaments Neurological disorders Neuronal-glial interactions Paraffin Embedding Peripheral nerves Proteins S100 protein S100 Proteins - metabolism Skin Neoplasms - pathology Smooth muscle Tumors
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