Clinical and immunologic outcomes following haplocompatible donor lymphocyte infusions

We retrospectively analyzed the characteristics of 16 consecutive pediatric patients who received one or more G-CSF-mobilized donor lymphocyte infusions (DLI) following a T-cell-depleted haplocompatible hematopoietic SCT (HSCT) to enhance immune recovery and/or treat an infection. The median time fr...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2009-12, Vol.44 (12), p.805-812
Hauptverfasser:	Dvorak, C C, Gilman, A L, Horn, B, Jaroscak, J, Dunn, E A, Baxter-Lowe, L A, Cowan, M J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adolescent Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood Donors Bone marrow, stem cells transplantation. Graft versus host reaction Cell Biology Child Child, Preschool Chronic Disease Confidence intervals Cytomegalovirus Cytomegalovirus - immunology Cytomegalovirus Infections - immunology Cytomegalovirus Infections - mortality Disease-Free Survival Female Graft vs Host Disease - blood Graft vs Host Disease - immunology Graft vs Host Disease - mortality Graft-versus-host reaction Granulocyte colony-stimulating factor Haplotypes Health aspects Hematologic Neoplasms - blood Hematologic Neoplasms - immunology Hematologic Neoplasms - mortality Hematologic Neoplasms - therapy Hematology Hematopoietic Stem Cell Transplantation Hematopoietic stem cells Humans Immune response Infant Infection Infections Internal Medicine Lymphocyte Transfusion Lymphocytes Lymphocytes T Male Medical sciences Medicine Medicine & Public Health original-article Patients Pediatrics Physiological aspects Prevention Public Health Recovery of Function - immunology Retrospective Studies Risk factors Severe Combined Immunodeficiency - blood Severe Combined Immunodeficiency - immunology Severe Combined Immunodeficiency - mortality Severe Combined Immunodeficiency - therapy Stem cell transplantation Stem Cells Survival Rate Time Factors Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation Transplantation, Homologous
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