Radiation Dose From Cone Beam CT in a Pediatric Phantom: Risk Estimation of Cancer Incidence
The objective of our study was to measure absorbed doses and calculate effective dose (ED) from cone beam CT (CBCT) with metal oxide semiconductor field effect transistor (MOSFET) detectors in an anthropomorphic phantom and to estimate the risk of cancer incidence for CBCT. Abdominal CBCT was perfor...
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| Veröffentlicht in: | American journal of roentgenology (1976) 2010-01, Vol.194 (1), p.186-190 |
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| creator | Kim, Sangroh Yoshizumi, Terry T Frush, Donald P Toncheva, Greta Yin, Fang-Fang |
| description | The objective of our study was to measure absorbed doses and calculate effective dose (ED) from cone beam CT (CBCT) with metal oxide semiconductor field effect transistor (MOSFET) detectors in an anthropomorphic phantom and to estimate the risk of cancer incidence for CBCT.
Abdominal CBCT was performed in an anthropomorphic phantom of a 5-year-old child using the On-Board Imager with arbitrarily designated standard-dose (125 kVp, 80 mA, 25 milliseconds) and low-dose (125 kVp, 40 mA, 10 milliseconds) modes. The full-fan mode was used, and 20 MOSFET dosimeters were used to measure the absorbed doses in various organs. We calculated the ED, the lifetime attributable risk (LAR) for cancer incidence, and relative risk (RR) of cancer induction from a single scan for both standard- and low-dose modes in 5-year-old children.
The highest absorbed doses were found in the skin, ascending colon, and stomach. The mean ED was 37.8+/-0.7 (SD) mSv for the standard-dose mode and 8.1+/-0.2 mSv for the low-dose mode. The LAR of cancer incidence ranged from 23 to 144 cases per 100,000 exposed persons for the standard-dose mode and from five to 31 cases per 100,000 exposed persons for the low-dose mode. The RR of cancer incidence ranged from 1.003 to 1.054 for the standard-dose mode and from 1.001 to 1.012 for the low-dose mode.
The ED from pediatric CBCT using the standard-dose mode was considerably higher than that of MDCT, whereas the ED for CBCT using the low-dose mode was comparable to that of abdominal MDCT. For abdominal CBCT in the pediatric phantom, the highest LARs were for colon and bladder cancers and the highest RRs were for stomach and liver cancers. |
| doi_str_mv | 10.2214/AJR.08.2168 |
| format | Article |
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Abdominal CBCT was performed in an anthropomorphic phantom of a 5-year-old child using the On-Board Imager with arbitrarily designated standard-dose (125 kVp, 80 mA, 25 milliseconds) and low-dose (125 kVp, 40 mA, 10 milliseconds) modes. The full-fan mode was used, and 20 MOSFET dosimeters were used to measure the absorbed doses in various organs. We calculated the ED, the lifetime attributable risk (LAR) for cancer incidence, and relative risk (RR) of cancer induction from a single scan for both standard- and low-dose modes in 5-year-old children.
The highest absorbed doses were found in the skin, ascending colon, and stomach. The mean ED was 37.8+/-0.7 (SD) mSv for the standard-dose mode and 8.1+/-0.2 mSv for the low-dose mode. The LAR of cancer incidence ranged from 23 to 144 cases per 100,000 exposed persons for the standard-dose mode and from five to 31 cases per 100,000 exposed persons for the low-dose mode. The RR of cancer incidence ranged from 1.003 to 1.054 for the standard-dose mode and from 1.001 to 1.012 for the low-dose mode.
The ED from pediatric CBCT using the standard-dose mode was considerably higher than that of MDCT, whereas the ED for CBCT using the low-dose mode was comparable to that of abdominal MDCT. For abdominal CBCT in the pediatric phantom, the highest LARs were for colon and bladder cancers and the highest RRs were for stomach and liver cancers.</description><identifier>ISSN: 0361-803X</identifier><identifier>EISSN: 1546-3141</identifier><identifier>DOI: 10.2214/AJR.08.2168</identifier><identifier>PMID: 20028922</identifier><identifier>CODEN: AAJRDX</identifier><language>eng</language><publisher>Reston, VA: Am Roentgen Ray Soc</publisher><subject>Applied radiobiology (equipment, dosimetry...) ; Biological and medical sciences ; Biological effects of radiation ; Body Burden ; Child, Preschool ; Fundamental and applied biological sciences. Psychology ; Humans ; Incidence ; Neoplasms, Radiation-Induced - epidemiology ; Neoplasms, Radiation-Induced - etiology ; Phantoms, Imaging ; Radiation Dosage ; Radiography, Abdominal ; Radiometry - methods ; Risk Assessment ; Tissues, organs and organisms biophysics ; Tomography, X-Ray Computed</subject><ispartof>American journal of roentgenology (1976), 2010-01, Vol.194 (1), p.186-190</ispartof><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c349t-146b06345f3c47e8d8a50351f78b2b548e86935adbd09171be2d425d7a47ae8a3</citedby><cites>FETCH-LOGICAL-c349t-146b06345f3c47e8d8a50351f78b2b548e86935adbd09171be2d425d7a47ae8a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010,4106,27900,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22336855$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20028922$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kim, Sangroh</creatorcontrib><creatorcontrib>Yoshizumi, Terry T</creatorcontrib><creatorcontrib>Frush, Donald P</creatorcontrib><creatorcontrib>Toncheva, Greta</creatorcontrib><creatorcontrib>Yin, Fang-Fang</creatorcontrib><title>Radiation Dose From Cone Beam CT in a Pediatric Phantom: Risk Estimation of Cancer Incidence</title><title>American journal of roentgenology (1976)</title><addtitle>AJR Am J Roentgenol</addtitle><description>The objective of our study was to measure absorbed doses and calculate effective dose (ED) from cone beam CT (CBCT) with metal oxide semiconductor field effect transistor (MOSFET) detectors in an anthropomorphic phantom and to estimate the risk of cancer incidence for CBCT.
Abdominal CBCT was performed in an anthropomorphic phantom of a 5-year-old child using the On-Board Imager with arbitrarily designated standard-dose (125 kVp, 80 mA, 25 milliseconds) and low-dose (125 kVp, 40 mA, 10 milliseconds) modes. The full-fan mode was used, and 20 MOSFET dosimeters were used to measure the absorbed doses in various organs. We calculated the ED, the lifetime attributable risk (LAR) for cancer incidence, and relative risk (RR) of cancer induction from a single scan for both standard- and low-dose modes in 5-year-old children.
The highest absorbed doses were found in the skin, ascending colon, and stomach. The mean ED was 37.8+/-0.7 (SD) mSv for the standard-dose mode and 8.1+/-0.2 mSv for the low-dose mode. The LAR of cancer incidence ranged from 23 to 144 cases per 100,000 exposed persons for the standard-dose mode and from five to 31 cases per 100,000 exposed persons for the low-dose mode. The RR of cancer incidence ranged from 1.003 to 1.054 for the standard-dose mode and from 1.001 to 1.012 for the low-dose mode.
The ED from pediatric CBCT using the standard-dose mode was considerably higher than that of MDCT, whereas the ED for CBCT using the low-dose mode was comparable to that of abdominal MDCT. For abdominal CBCT in the pediatric phantom, the highest LARs were for colon and bladder cancers and the highest RRs were for stomach and liver cancers.</description><subject>Applied radiobiology (equipment, dosimetry...)</subject><subject>Biological and medical sciences</subject><subject>Biological effects of radiation</subject><subject>Body Burden</subject><subject>Child, Preschool</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Incidence</subject><subject>Neoplasms, Radiation-Induced - epidemiology</subject><subject>Neoplasms, Radiation-Induced - etiology</subject><subject>Phantoms, Imaging</subject><subject>Radiation Dosage</subject><subject>Radiography, Abdominal</subject><subject>Radiometry - methods</subject><subject>Risk Assessment</subject><subject>Tissues, organs and organisms biophysics</subject><subject>Tomography, X-Ray Computed</subject><issn>0361-803X</issn><issn>1546-3141</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0DtPwzAUBWALgaA8JnbkBRhQip-JwwblLSRQBRIDkuUkN9SQxMVOVfHvcdUCk-_w3XPlg9A-JUPGqDg9vx8PiRoymqo1NKBSpAmngq6jAeEpTRThr1toO4QPQkim8mwTbTFCmMoZG6C3sams6a3r8KULgK-9a_HIdYAvwMTpGdsOG_wEC-VtiZ8mputde4bHNnziq9DbdrnuajwyXQke33WlrSCOu2ijNk2AvdW7g16ur55Ht8nD483d6PwhKbnI-4SKtCApF7LmpchAVcpIwiWtM1WwQgoFKs25NFVRkZxmtABWCSarzIjMgDJ8Bx0vc6fefc0g9Lq1oYSmMR24WdAZF4wIxXiUJ0tZeheCh1pPffyA_9aU6EWbOrapidKLNqM-WOXOihaqP_tbXwSHK2BCaZraxwJs-HfxYqqkjO5o6Sb2fTK3HnRoTdPEWKrn8znNhaaaqpT_AN1bh2k</recordid><startdate>20100101</startdate><enddate>20100101</enddate><creator>Kim, Sangroh</creator><creator>Yoshizumi, Terry T</creator><creator>Frush, Donald P</creator><creator>Toncheva, Greta</creator><creator>Yin, Fang-Fang</creator><general>Am Roentgen Ray Soc</general><general>American Roentgen Ray Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20100101</creationdate><title>Radiation Dose From Cone Beam CT in a Pediatric Phantom: Risk Estimation of Cancer Incidence</title><author>Kim, Sangroh ; Yoshizumi, Terry T ; Frush, Donald P ; Toncheva, Greta ; Yin, Fang-Fang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c349t-146b06345f3c47e8d8a50351f78b2b548e86935adbd09171be2d425d7a47ae8a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Applied radiobiology (equipment, dosimetry...)</topic><topic>Biological and medical sciences</topic><topic>Biological effects of radiation</topic><topic>Body Burden</topic><topic>Child, Preschool</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>Incidence</topic><topic>Neoplasms, Radiation-Induced - epidemiology</topic><topic>Neoplasms, Radiation-Induced - etiology</topic><topic>Phantoms, Imaging</topic><topic>Radiation Dosage</topic><topic>Radiography, Abdominal</topic><topic>Radiometry - methods</topic><topic>Risk Assessment</topic><topic>Tissues, organs and organisms biophysics</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kim, Sangroh</creatorcontrib><creatorcontrib>Yoshizumi, Terry T</creatorcontrib><creatorcontrib>Frush, Donald P</creatorcontrib><creatorcontrib>Toncheva, Greta</creatorcontrib><creatorcontrib>Yin, Fang-Fang</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of roentgenology (1976)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, Sangroh</au><au>Yoshizumi, Terry T</au><au>Frush, Donald P</au><au>Toncheva, Greta</au><au>Yin, Fang-Fang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Radiation Dose From Cone Beam CT in a Pediatric Phantom: Risk Estimation of Cancer Incidence</atitle><jtitle>American journal of roentgenology (1976)</jtitle><addtitle>AJR Am J Roentgenol</addtitle><date>2010-01-01</date><risdate>2010</risdate><volume>194</volume><issue>1</issue><spage>186</spage><epage>190</epage><pages>186-190</pages><issn>0361-803X</issn><eissn>1546-3141</eissn><coden>AAJRDX</coden><abstract>The objective of our study was to measure absorbed doses and calculate effective dose (ED) from cone beam CT (CBCT) with metal oxide semiconductor field effect transistor (MOSFET) detectors in an anthropomorphic phantom and to estimate the risk of cancer incidence for CBCT.
Abdominal CBCT was performed in an anthropomorphic phantom of a 5-year-old child using the On-Board Imager with arbitrarily designated standard-dose (125 kVp, 80 mA, 25 milliseconds) and low-dose (125 kVp, 40 mA, 10 milliseconds) modes. The full-fan mode was used, and 20 MOSFET dosimeters were used to measure the absorbed doses in various organs. We calculated the ED, the lifetime attributable risk (LAR) for cancer incidence, and relative risk (RR) of cancer induction from a single scan for both standard- and low-dose modes in 5-year-old children.
The highest absorbed doses were found in the skin, ascending colon, and stomach. The mean ED was 37.8+/-0.7 (SD) mSv for the standard-dose mode and 8.1+/-0.2 mSv for the low-dose mode. The LAR of cancer incidence ranged from 23 to 144 cases per 100,000 exposed persons for the standard-dose mode and from five to 31 cases per 100,000 exposed persons for the low-dose mode. The RR of cancer incidence ranged from 1.003 to 1.054 for the standard-dose mode and from 1.001 to 1.012 for the low-dose mode.
The ED from pediatric CBCT using the standard-dose mode was considerably higher than that of MDCT, whereas the ED for CBCT using the low-dose mode was comparable to that of abdominal MDCT. For abdominal CBCT in the pediatric phantom, the highest LARs were for colon and bladder cancers and the highest RRs were for stomach and liver cancers.</abstract><cop>Reston, VA</cop><pub>Am Roentgen Ray Soc</pub><pmid>20028922</pmid><doi>10.2214/AJR.08.2168</doi><tpages>5</tpages></addata></record> |
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| source | American Roentgen Ray Society; MEDLINE; Alma/SFX Local Collection |
| subjects | Applied radiobiology (equipment, dosimetry...) Biological and medical sciences Biological effects of radiation Body Burden Child, Preschool Fundamental and applied biological sciences. Psychology Humans Incidence Neoplasms, Radiation-Induced - epidemiology Neoplasms, Radiation-Induced - etiology Phantoms, Imaging Radiation Dosage Radiography, Abdominal Radiometry - methods Risk Assessment Tissues, organs and organisms biophysics Tomography, X-Ray Computed |
| title | Radiation Dose From Cone Beam CT in a Pediatric Phantom: Risk Estimation of Cancer Incidence |
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