Repairing of Infarcted Myocardium Using a Novel Cell Patch Therapy

A 54-year-old man underwent left anterior descending artery bypass grafting with cell patch therapy for myocardial infarction. We applied a novel approach to replicating the infarcted myocardium by anchoring polyglycolic acid felt seeded with autologous peripheral blood mononuclear cells in front of...

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Veröffentlicht in:	Asian cardiovascular & thoracic annals 2009-12, Vol.17 (6), p.643-646
Hauptverfasser:	Yokomuro, Hiroki, Ichikawa, Yukio, Shiono, Noritsugu, Kajiwara, Hirokazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiac Surgical Procedures Coronary Artery Bypass Coronary Vessels - physiopathology Humans Leukocytes, Mononuclear - transplantation Male Middle Aged Myocardial Infarction - diagnosis Myocardial Infarction - physiopathology Myocardial Infarction - surgery Myocardium - pathology Neovascularization, Physiologic Polyglycolic Acid Regeneration Time Factors Tissue Scaffolds Tomography, Emission-Computed, Single-Photon Tomography, X-Ray Computed Transplantation, Autologous Treatment Outcome
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Zusammenfassung:	A 54-year-old man underwent left anterior descending artery bypass grafting with cell patch therapy for myocardial infarction. We applied a novel approach to replicating the infarcted myocardium by anchoring polyglycolic acid felt seeded with autologous peripheral blood mononuclear cells in front of the infarcted area. The cell patch remained fixed to the myocardium for 1 month, and the infarcted myocardium was reperfused.
ISSN:	0218-4923 1816-5370
DOI:	10.1177/0218492309338102