Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle

The possible functional role of transient receptor potential (TRP) channels was investigated by testing various TRP agonists and antagonists in an isolated rat sinus hair follicle preparation. Extracellular recordings from slowly adapting type II mechanoreceptor units were made. The antagonist capsa...

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Veröffentlicht in:	Journal of the peripheral nervous system 2009-12, Vol.14 (4), p.300-309
1. Verfasser:	Cahusac, Peter M.B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrolein - administration & dosage Acrolein - analogs & derivatives Acrolein - pharmacology Action Potentials - drug effects Animals Ankyrins Calcium Channels - metabolism camphor Camphor - administration & dosage Camphor - pharmacology capsaicin Capsaicin - administration & dosage Capsaicin - analogs & derivatives Capsaicin - pharmacology capsazepine cinnamaldehyde Evoked Potentials - drug effects Hair Follicle - drug effects Hair Follicle - physiology icilin In Vitro Techniques Isothiocyanates - administration & dosage Isothiocyanates - pharmacology Male mechanogated channels Mechanoreceptors - drug effects Mechanoreceptors - physiology Menthol - pharmacology Physical Stimulation Pyrimidinones - administration & dosage Pyrimidinones - pharmacology Rats Rats, Wistar ruthenium red Ruthenium Red - pharmacology tetraethylammonium Time Factors Transient Receptor Potential Channels - agonists Transient Receptor Potential Channels - antagonists & inhibitors Transient Receptor Potential Channels - metabolism TRPA1 Cation Channel TRPC Cation Channels TRPV Cation Channels - agonists TRPV Cation Channels - antagonists & inhibitors TRPV Cation Channels - metabolism
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