Antioxidant, free radical-scavenging, and NF-kappaB-inhibitory activities of phytosteryl ferulates: structure-activity studies

Some of the pharmacological properties of phytosteryl ferulates may be linked to their antioxidant potential. In this study, 2,2-diphenyl-1-picrylhydrazyl (DPPH), electron spin resonance (ESR), and thiobarbituric acid-reactive substances (TBARS) assays demonstrated that phytosteryl ferulates such as...

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Veröffentlicht in:	Journal of pharmacological sciences 2009-12, Vol.111 (4), p.328-337
Hauptverfasser:	Islam, Md Shafiqul, Yoshida, Hiroshi, Matsuki, Naoaki, Ono, Kenichiro, Nagasaka, Reiko, Ushio, Hideki, Guo, Ying, Hiramatsu, Toshiyuki, Hosoya, Takamitsu, Murata, Takahisa, Hori, Masatoshi, Ozaki, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents, Non-Steroidal - pharmacology Antioxidants - pharmacology Cell Line Coumaric Acids - chemistry Coumaric Acids - pharmacology Free Radical Scavengers - pharmacology Macrophages - drug effects Macrophages - metabolism Membranes, Artificial Mice NF-kappa B - antagonists & inhibitors NIH 3T3 Cells Phenylpropionates - chemistry Phenylpropionates - pharmacology Phytosterols - chemistry Phytosterols - pharmacology Reactive Oxygen Species - antagonists & inhibitors Structure-Activity Relationship
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