Systemic and airway inflammation in sleep apnea and obesity: the role of ICAM-1 and IL-8

The recurrent hypoxic stress that characterizes obstructive sleep apnea (OSA) seems to play a role in the increased adherence of neutrophils to endothelial cells as well as in the resulting migration of the former to the inflamed area. Intercellular adhesion molecule 1 (ICAM-1) and interleukin (IL)-...

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Veröffentlicht in:	Translational research : the journal of laboratory and clinical medicine 2010, Vol.155 (1), p.35-43
Hauptverfasser:	Carpagnano, Giovanna E, Spanevello, Antonio, Sabato, Roberto, Depalo, Annarita, Palladino, Grazia P, Bergantino, Laura, Foschino Barbaro, Maria P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Asthma - etiology Biological and medical sciences Breath Tests Cell Count Female General aspects Humans Inflammation - etiology Intercellular Adhesion Molecule-1 - analysis Intercellular Adhesion Molecule-1 - physiology Interleukin-8 - analysis Interleukin-8 - physiology Internal Medicine Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Middle Aged Neutrophils - physiology Obesity - complications Obesity - immunology Pneumology Respiratory system : syndromes and miscellaneous diseases Sleep Apnea, Obstructive - complications Sleep Apnea, Obstructive - immunology Sputum - cytology
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