Estimation of coronary heart disease risk in Chilean subjects based on adapted Framingham equations
Cardiovascular disease is the leading cause of morbidity and mortality in Chile and worldwide. Framingham functions were developed to calculate overall coronary heart disease risk. However these functions overestimate the risk in some countries like Chile. To develop Chilean risk tables to assess th...
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| Veröffentlicht in: | Revista medíca de Chile 2009-10, Vol.137 (10), p.1273-1282 |
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| container_title | Revista medíca de Chile |
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| creator | Icaza, Gloria Núñez, Loreto Marrugat, Jaume Mujica, Verónica Escobar, M Cristina Jiménez, Ana Luisa Pérez, Paulina Palomo, Iván |
| description | Cardiovascular disease is the leading cause of morbidity and mortality in Chile and worldwide. Framingham functions were developed to calculate overall coronary heart disease risk. However these functions overestimate the risk in some countries like Chile.
To develop Chilean risk tables to assess the overall 10-year risk of coronary heart disease.
The Framingham function was adapted for a population aged 35 to 74 years, based on an estimate of Chilean incidence of coronary heart disease and the prevalence of coronary heart disease risk factors such as age, sex, total cholesterol, high-density lipoprotein cholesterol, blood pressure, diabetes and smoking.
The 10-year incidence of coronary heart disease in Chile (2.7% in men, 1.096 in women) was lower than the incidence in the United States (10.096/3.896) and Spain (4.996/2.296), but higher than China (1.196/0.496). Framingham tables have more than 50% of cells in the risk category of 10% or greater. In contrast, Chilean tables have less than 10% of cells in the same risk category.
Adapted tables use local information to calculate overall coronary heart disease risk. A validation study should be conducted to assess their predictive power. |
| format | Article |
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To develop Chilean risk tables to assess the overall 10-year risk of coronary heart disease.
The Framingham function was adapted for a population aged 35 to 74 years, based on an estimate of Chilean incidence of coronary heart disease and the prevalence of coronary heart disease risk factors such as age, sex, total cholesterol, high-density lipoprotein cholesterol, blood pressure, diabetes and smoking.
The 10-year incidence of coronary heart disease in Chile (2.7% in men, 1.096 in women) was lower than the incidence in the United States (10.096/3.896) and Spain (4.996/2.296), but higher than China (1.196/0.496). Framingham tables have more than 50% of cells in the risk category of 10% or greater. In contrast, Chilean tables have less than 10% of cells in the same risk category.
Adapted tables use local information to calculate overall coronary heart disease risk. A validation study should be conducted to assess their predictive power.</description><identifier>ISSN: 0034-9887</identifier><identifier>PMID: 20011933</identifier><language>spa</language><publisher>Chile</publisher><subject>Adult ; Aged ; Chile - epidemiology ; China - epidemiology ; Coronary Disease - epidemiology ; Coronary Disease - etiology ; Diabetes Complications - epidemiology ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Prevalence ; Risk Assessment - methods ; Risk Factors ; Sex Distribution ; Spain - epidemiology ; United States - epidemiology</subject><ispartof>Revista medíca de Chile, 2009-10, Vol.137 (10), p.1273-1282</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20011933$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Icaza, Gloria</creatorcontrib><creatorcontrib>Núñez, Loreto</creatorcontrib><creatorcontrib>Marrugat, Jaume</creatorcontrib><creatorcontrib>Mujica, Verónica</creatorcontrib><creatorcontrib>Escobar, M Cristina</creatorcontrib><creatorcontrib>Jiménez, Ana Luisa</creatorcontrib><creatorcontrib>Pérez, Paulina</creatorcontrib><creatorcontrib>Palomo, Iván</creatorcontrib><title>Estimation of coronary heart disease risk in Chilean subjects based on adapted Framingham equations</title><title>Revista medíca de Chile</title><addtitle>Rev Med Chil</addtitle><description>Cardiovascular disease is the leading cause of morbidity and mortality in Chile and worldwide. Framingham functions were developed to calculate overall coronary heart disease risk. However these functions overestimate the risk in some countries like Chile.
To develop Chilean risk tables to assess the overall 10-year risk of coronary heart disease.
The Framingham function was adapted for a population aged 35 to 74 years, based on an estimate of Chilean incidence of coronary heart disease and the prevalence of coronary heart disease risk factors such as age, sex, total cholesterol, high-density lipoprotein cholesterol, blood pressure, diabetes and smoking.
The 10-year incidence of coronary heart disease in Chile (2.7% in men, 1.096 in women) was lower than the incidence in the United States (10.096/3.896) and Spain (4.996/2.296), but higher than China (1.196/0.496). Framingham tables have more than 50% of cells in the risk category of 10% or greater. In contrast, Chilean tables have less than 10% of cells in the same risk category.
Adapted tables use local information to calculate overall coronary heart disease risk. A validation study should be conducted to assess their predictive power.</description><subject>Adult</subject><subject>Aged</subject><subject>Chile - epidemiology</subject><subject>China - epidemiology</subject><subject>Coronary Disease - epidemiology</subject><subject>Coronary Disease - etiology</subject><subject>Diabetes Complications - epidemiology</subject><subject>Female</subject><subject>Humans</subject><subject>Incidence</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prevalence</subject><subject>Risk Assessment - methods</subject><subject>Risk Factors</subject><subject>Sex Distribution</subject><subject>Spain - epidemiology</subject><subject>United States - epidemiology</subject><issn>0034-9887</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kD1PwzAYhD2AaCn8BeSNKZJjp7E9oqoFpEosMEev7dfUJV-1naH_ngja6U665264G7JkTFSFVkouyH1KR8a4rEt1RxacsbLUQiyJ3aYcOshh6OngqR3i0EM80wNCzNSFhJCQxpB-aOjp5hBahJ6myRzR5kTNnDo6d8HBmGe7i9CF_vsAHcXT9LebHsithzbh40VX5Gu3_dy8FfuP1_fNy74Yy4rlwnljtVTAba2MA82N92sG4Cw6UzJruHKcCe4kWqUU-LX2zknBFZPSGxAr8vy_O8bhNGHKTReSxbaFHocpNVJUpa5lrWfy6UJOpkPXjHH-IJ6b6y_iFwNtYJc</recordid><startdate>200910</startdate><enddate>200910</enddate><creator>Icaza, Gloria</creator><creator>Núñez, Loreto</creator><creator>Marrugat, Jaume</creator><creator>Mujica, Verónica</creator><creator>Escobar, M Cristina</creator><creator>Jiménez, Ana Luisa</creator><creator>Pérez, Paulina</creator><creator>Palomo, Iván</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200910</creationdate><title>Estimation of coronary heart disease risk in Chilean subjects based on adapted Framingham equations</title><author>Icaza, Gloria ; Núñez, Loreto ; Marrugat, Jaume ; Mujica, Verónica ; Escobar, M Cristina ; Jiménez, Ana Luisa ; Pérez, Paulina ; Palomo, Iván</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p140t-dfbc978a2c68bda92bff50aadcedb10cb28d2032d7ec888af59fdd7328077fba3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>spa</language><creationdate>2009</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Chile - epidemiology</topic><topic>China - epidemiology</topic><topic>Coronary Disease - epidemiology</topic><topic>Coronary Disease - etiology</topic><topic>Diabetes Complications - epidemiology</topic><topic>Female</topic><topic>Humans</topic><topic>Incidence</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Prevalence</topic><topic>Risk Assessment - methods</topic><topic>Risk Factors</topic><topic>Sex Distribution</topic><topic>Spain - epidemiology</topic><topic>United States - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Icaza, Gloria</creatorcontrib><creatorcontrib>Núñez, Loreto</creatorcontrib><creatorcontrib>Marrugat, Jaume</creatorcontrib><creatorcontrib>Mujica, Verónica</creatorcontrib><creatorcontrib>Escobar, M Cristina</creatorcontrib><creatorcontrib>Jiménez, Ana Luisa</creatorcontrib><creatorcontrib>Pérez, Paulina</creatorcontrib><creatorcontrib>Palomo, Iván</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Revista medíca de Chile</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Icaza, Gloria</au><au>Núñez, Loreto</au><au>Marrugat, Jaume</au><au>Mujica, Verónica</au><au>Escobar, M Cristina</au><au>Jiménez, Ana Luisa</au><au>Pérez, Paulina</au><au>Palomo, Iván</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Estimation of coronary heart disease risk in Chilean subjects based on adapted Framingham equations</atitle><jtitle>Revista medíca de Chile</jtitle><addtitle>Rev Med Chil</addtitle><date>2009-10</date><risdate>2009</risdate><volume>137</volume><issue>10</issue><spage>1273</spage><epage>1282</epage><pages>1273-1282</pages><issn>0034-9887</issn><abstract>Cardiovascular disease is the leading cause of morbidity and mortality in Chile and worldwide. Framingham functions were developed to calculate overall coronary heart disease risk. However these functions overestimate the risk in some countries like Chile.
To develop Chilean risk tables to assess the overall 10-year risk of coronary heart disease.
The Framingham function was adapted for a population aged 35 to 74 years, based on an estimate of Chilean incidence of coronary heart disease and the prevalence of coronary heart disease risk factors such as age, sex, total cholesterol, high-density lipoprotein cholesterol, blood pressure, diabetes and smoking.
The 10-year incidence of coronary heart disease in Chile (2.7% in men, 1.096 in women) was lower than the incidence in the United States (10.096/3.896) and Spain (4.996/2.296), but higher than China (1.196/0.496). Framingham tables have more than 50% of cells in the risk category of 10% or greater. In contrast, Chilean tables have less than 10% of cells in the same risk category.
Adapted tables use local information to calculate overall coronary heart disease risk. A validation study should be conducted to assess their predictive power.</abstract><cop>Chile</cop><pmid>20011933</pmid><tpages>10</tpages></addata></record> |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Aged Chile - epidemiology China - epidemiology Coronary Disease - epidemiology Coronary Disease - etiology Diabetes Complications - epidemiology Female Humans Incidence Male Middle Aged Prevalence Risk Assessment - methods Risk Factors Sex Distribution Spain - epidemiology United States - epidemiology |
| title | Estimation of coronary heart disease risk in Chilean subjects based on adapted Framingham equations |
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