Anti-diabetic and hypoglycaemic effects of Momordica charantia (bitter melon): a mini review
It has been estimated that up to one-third of patients with diabetes mellitus use some form of complementary and alternative medicine. Momordica charantia (bitter melon) is a popular fruit used for the treatment of diabetes and related conditions amongst the indigenous populations of Asia, South Ame...
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| Veröffentlicht in: | British journal of nutrition 2009-12, Vol.102 (12), p.1703-1708 |
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| container_title | British journal of nutrition |
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| creator | Leung, Lawrence Birtwhistle, Richard Kotecha, Jyoti Hannah, Susan Cuthbertson, Sharon |
| description | It has been estimated that up to one-third of patients with diabetes mellitus use some form of complementary and alternative medicine. Momordica charantia (bitter melon) is a popular fruit used for the treatment of diabetes and related conditions amongst the indigenous populations of Asia, South America, India and East Africa. Abundant pre-clinical studies have documented the anti-diabetic and hypoglycaemic effects of M. charantia through various postulated mechanisms. However, clinical trial data with human subjects are limited and flawed by poor study design and low statistical power. The present article reviews the clinical data regarding the anti-diabetic potentials of M. charantia and calls for better-designed clinical trials to further elucidate its possible therapeutic effects. |
| doi_str_mv | 10.1017/S0007114509992054 |
| format | Article |
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Momordica charantia (bitter melon) is a popular fruit used for the treatment of diabetes and related conditions amongst the indigenous populations of Asia, South America, India and East Africa. Abundant pre-clinical studies have documented the anti-diabetic and hypoglycaemic effects of M. charantia through various postulated mechanisms. However, clinical trial data with human subjects are limited and flawed by poor study design and low statistical power. 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Momordica charantia (bitter melon) is a popular fruit used for the treatment of diabetes and related conditions amongst the indigenous populations of Asia, South America, India and East Africa. Abundant pre-clinical studies have documented the anti-diabetic and hypoglycaemic effects of M. charantia through various postulated mechanisms. However, clinical trial data with human subjects are limited and flawed by poor study design and low statistical power. The present article reviews the clinical data regarding the anti-diabetic potentials of M. charantia and calls for better-designed clinical trials to further elucidate its possible therapeutic effects.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>19825210</pmid><doi>10.1017/S0007114509992054</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | AMP-Activated Protein Kinases animal models Animals case studies Clinical Trials as Topic Complementary and alternative medicine Diabetes mellitus Diabetes Mellitus, Type 1 - drug therapy Diabetes Mellitus, Type 2 - drug therapy dietary supplements Female Fruit - chemistry functional foods Humans Hypoglycaemic agents hypoglycemic agents Hypoglycemic Agents - administration & dosage literature reviews Male medicinal plants Momordica charantia Momordica charantia - adverse effects Momordica charantia - chemistry phytochemicals Phytotherapy Plant Extracts - administration & dosage Plant Leaves - chemistry postprandial state Randomized Controlled Trials as Topic Rats Seeds - chemistry toxicity traditional medicine Triterpenes - analysis |
| title | Anti-diabetic and hypoglycaemic effects of Momordica charantia (bitter melon): a mini review |
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