Conserved MicroRNA miR-8/miR-200 and Its Target USH/FOG2 Control Growth by Regulating PI3K

How body size is determined is a long-standing question in biology, yet its regulatory mechanisms remain largely unknown. Here, we find that a conserved microRNA miR-8 and its target, USH, regulate body size in Drosophila. miR-8 null flies are smaller in size and defective in insulin signaling in fa...

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Veröffentlicht in:Cell 2009-12, Vol.139 (6), p.1096-1108
Hauptverfasser: Hyun, Seogang, Lee, Jung Hyun, Jin, Hua, Nam, JinWu, Namkoong, Bumjin, Lee, Gina, Chung, Jongkyeong, Kim, V. Narry
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Sprache:eng
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