Immunotherapy with the saponin enriched-Leishmune® vaccine versus immunochemotherapy in dogs with natural canine visceral leishmaniasis

Abstract Leishmune® , the first licensed vaccine for prophylaxis against canine visceral leishmaniasis (CVL) and is also immunotherapeutic when used with double saponin adjuvant concentration. The Leishmune® therapeutic vaccine was assessed for immunotherapy (IT) in 31 infected dogs and for immunoch...

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Veröffentlicht in:	Vaccine 2010-01, Vol.28 (3), p.597-603
Hauptverfasser:	Borja-Cabrera, G.P, Santos, F.N, Santos, F.B, Trivellato, Fernando Antonio de A, Kawasaki, Jarbas Kiyoshi A, Costa, Andreia Cerqueira, Castro, Tatiana, Nogueira, F.S, Moreira, M.A.B, Luvizotto, M.C.R, Palatnik, M, Palatnik-de-Sousa, C.B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - therapeutic use Allergy and Immunology Allopurinol Allopurinol - therapeutic use Amphotericin B Amphotericin B - therapeutic use Animals Antiprotozoal Agents Applied microbiology Biological and medical sciences Canine visceral leishmaniasis Dog Diseases - pathology Dog Diseases - therapy Dogs Drug Therapy - methods Drug Therapy, Combination Follow-Up Studies Fundamental and applied biological sciences. Psychology Human protozoal diseases Immunochemotherapy Immunotherapy Immunotherapy - methods Infectious diseases Kala-azar Leishmania Leishmania chagasi Leishmaniasis, Visceral - pathology Leishmaniasis, Visceral - therapy Leishmaniasis, Visceral - veterinary Leishmune Leshmaniasis Lymph Nodes - parasitology Medical sciences Microbiology Parasitic diseases Protozoal diseases Protozoan Vaccines - therapeutic use Saponin Saponins - therapeutic use Survival Analysis Treatment Outcome Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
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