Basal pulmonary vascular resistance and nitric oxide responsiveness late after fontan-type operation

The pulsatile nature of pulmonary blood flow is important for shear stress-mediated release of endothelium-derived nitric oxide (NO) and lowering pulmonary vascular resistance (PVR) by passive recruitment of capillaries. Normal pulsatile flow is lost or markedly attenuated after Fontan-type operatio...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2003-07, Vol.107 (25), p.3204-3208
Hauptverfasser:	KHAMBADKONE, S, LI, J, DE LEVAL, M. R, CULLEN, S, DEANFIELD, J. E, REDINGTON, A. N
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Adolescent Age Factors Angiography Biological and medical sciences Blood Flow Velocity - drug effects Blood Flow Velocity - physiology Cardiac Catheterization Child Endothelium, Vascular - drug effects Endothelium, Vascular - physiology Female Fontan Procedure Heart Defects, Congenital - surgery Hemodynamics - drug effects Hemodynamics - physiology Humans Male Medical sciences Nitric Oxide - administration & dosage Oxygen Consumption - physiology Pulmonary Circulation - drug effects Pulmonary Circulation - physiology Pulsatile Flow - physiology Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart Time Vascular Resistance - drug effects Vascular Resistance - physiology
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