The use of lead follicle diameter to initiate gonadotropin-releasing hormone antagonist does not affect in vitro fertilization clinical pregnancy, implantation, or live birth rates: a prospective, randomized study
In this prospective, randomized study, waiting for the lead follicle to reach 14 mm before initiating GnRH antagonist administration effectively prevents an LH surge and ovulation during an IVF cycle. Furthermore, delaying GnRH start until the dominant follicle reaches 14 mm neither impacts the clin...
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Veröffentlicht in: | Fertility and sterility 2009-12, Vol.92 (6), p.2047-2049 |
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container_title | Fertility and sterility |
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creator | Dayal, Molina B., M.D., M.P.H Frankfurter, David, M.D O'Hern, Candice, M.D Peak, Douglas, B.S Dubey, Anil, Ph.D Gindoff, Paul R., M.D |
description | In this prospective, randomized study, waiting for the lead follicle to reach 14 mm before initiating GnRH antagonist administration effectively prevents an LH surge and ovulation during an IVF cycle. Furthermore, delaying GnRH start until the dominant follicle reaches 14 mm neither impacts the clinical pregnancy, implantation, or live birth rates nor increases the incidence of severe ovarian hyperstimulation syndrome. |
doi_str_mv | 10.1016/j.fertnstert.2009.05.083 |
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Obstetrics ; Humans ; Infant, Newborn ; Internal Medicine ; Luteinizing Hormone - metabolism ; Medical sciences ; Obstetrics and Gynecology ; Ovarian Follicle - anatomy & histology ; Ovarian Hyperstimulation Syndrome - prevention & control ; Ovulation - drug effects ; Pregnancy ; Pregnancy Outcome ; Prospective Studies ; Time Factors</subject><ispartof>Fertility and sterility, 2009-12, Vol.92 (6), p.2047-2049</ispartof><rights>American Society for Reproductive Medicine</rights><rights>2009 American Society for Reproductive Medicine</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c508t-bf496c82c36970a2bfe322ab9401840bcde150f9d80a3dff3a4815e29e6781ad3</citedby><cites>FETCH-LOGICAL-c508t-bf496c82c36970a2bfe322ab9401840bcde150f9d80a3dff3a4815e29e6781ad3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.fertnstert.2009.05.083$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3538,27906,27907,45977</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22249873$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19591990$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dayal, Molina B., M.D., M.P.H</creatorcontrib><creatorcontrib>Frankfurter, David, M.D</creatorcontrib><creatorcontrib>O'Hern, Candice, M.D</creatorcontrib><creatorcontrib>Peak, Douglas, B.S</creatorcontrib><creatorcontrib>Dubey, Anil, Ph.D</creatorcontrib><creatorcontrib>Gindoff, Paul R., M.D</creatorcontrib><title>The use of lead follicle diameter to initiate gonadotropin-releasing hormone antagonist does not affect in vitro fertilization clinical pregnancy, implantation, or live birth rates: a prospective, randomized study</title><title>Fertility and sterility</title><addtitle>Fertil Steril</addtitle><description>In this prospective, randomized study, waiting for the lead follicle to reach 14 mm before initiating GnRH antagonist administration effectively prevents an LH surge and ovulation during an IVF cycle. Furthermore, delaying GnRH start until the dominant follicle reaches 14 mm neither impacts the clinical pregnancy, implantation, or live birth rates nor increases the incidence of severe ovarian hyperstimulation syndrome.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Birth Rate</subject><subject>Embryo Implantation</subject><subject>Female</subject><subject>Fertilization in Vitro - methods</subject><subject>Gonadotropin-Releasing Hormone - antagonists & inhibitors</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Internal Medicine</subject><subject>Luteinizing Hormone - metabolism</subject><subject>Medical sciences</subject><subject>Obstetrics and Gynecology</subject><subject>Ovarian Follicle - anatomy & histology</subject><subject>Ovarian Hyperstimulation Syndrome - prevention & control</subject><subject>Ovulation - drug effects</subject><subject>Pregnancy</subject><subject>Pregnancy Outcome</subject><subject>Prospective Studies</subject><subject>Time Factors</subject><issn>0015-0282</issn><issn>1556-5653</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNks1uEzEUhUcIREvhFdDdIDZJsD3_LJBKxZ9UiQVlbXns68Rhxg62Eyl9T96HO0qgEis2tmR_9_joHBcFcLbijDdvtiuLMfuUaV0JxvoVq1esKx8Vl7yum2Xd1OXj4pIxXi-Z6MRF8SylLWOs4a14Wlzwvu5537PL4tfdBmGfEIKFEZUBG8bR6RHBODUhPQA5gPMuO5UR1sErE3IMO-eXEWkiOb-GTYhT8AjKZ0WISxlMwAQ-ZFDWos4kAQdHgzA7d6O7V9kFD3okba1G2EVce-X1cQFu2o2z0gwsIEQY3QFhcDFvIJKL9BYU8SHtSJiuFnTqTZjcPRpIeW-Oz4snVo0JX5z3q-L7xw93N5-Xt18_fbm5vl3qmnV5Odiqb3QndNn0LVNisFgKoYa-Yryr2KAN8prZ3nRMlcbaUlUdr1H02LQdV6a8Kl6fdMnNzz2mLCeXNI5kH8M-ybasKHBeCiK7E6nJd4po5S66ScWj5EzOncqtfOhUzp1KVkvqlEZfnh_ZDxOah8FziQS8OgMqUZSW0tAu_eWEEFXftbPQ-xOHFMnBYZRJO_QajYuUpDTB_Y-bd_-I_KnwBx4xbcM-eopccpmEZPLb_AfnL8h6xoXgbfkbbcjg4g</recordid><startdate>20091201</startdate><enddate>20091201</enddate><creator>Dayal, Molina B., M.D., M.P.H</creator><creator>Frankfurter, David, M.D</creator><creator>O'Hern, Candice, M.D</creator><creator>Peak, Douglas, B.S</creator><creator>Dubey, Anil, Ph.D</creator><creator>Gindoff, Paul R., M.D</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20091201</creationdate><title>The use of lead follicle diameter to initiate gonadotropin-releasing hormone antagonist does not affect in vitro fertilization clinical pregnancy, implantation, or live birth rates: a prospective, randomized study</title><author>Dayal, Molina B., M.D., M.P.H ; Frankfurter, David, M.D ; O'Hern, Candice, M.D ; Peak, Douglas, B.S ; Dubey, Anil, Ph.D ; Gindoff, Paul R., M.D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c508t-bf496c82c36970a2bfe322ab9401840bcde150f9d80a3dff3a4815e29e6781ad3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Birth Rate</topic><topic>Embryo Implantation</topic><topic>Female</topic><topic>Fertilization in Vitro - methods</topic><topic>Gonadotropin-Releasing Hormone - antagonists & inhibitors</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Internal Medicine</topic><topic>Luteinizing Hormone - metabolism</topic><topic>Medical sciences</topic><topic>Obstetrics and Gynecology</topic><topic>Ovarian Follicle - anatomy & histology</topic><topic>Ovarian Hyperstimulation Syndrome - prevention & control</topic><topic>Ovulation - drug effects</topic><topic>Pregnancy</topic><topic>Pregnancy Outcome</topic><topic>Prospective Studies</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dayal, Molina B., M.D., M.P.H</creatorcontrib><creatorcontrib>Frankfurter, David, M.D</creatorcontrib><creatorcontrib>O'Hern, Candice, M.D</creatorcontrib><creatorcontrib>Peak, Douglas, B.S</creatorcontrib><creatorcontrib>Dubey, Anil, Ph.D</creatorcontrib><creatorcontrib>Gindoff, Paul R., M.D</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Fertility and sterility</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dayal, Molina B., M.D., M.P.H</au><au>Frankfurter, David, M.D</au><au>O'Hern, Candice, M.D</au><au>Peak, Douglas, B.S</au><au>Dubey, Anil, Ph.D</au><au>Gindoff, Paul R., M.D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The use of lead follicle diameter to initiate gonadotropin-releasing hormone antagonist does not affect in vitro fertilization clinical pregnancy, implantation, or live birth rates: a prospective, randomized study</atitle><jtitle>Fertility and sterility</jtitle><addtitle>Fertil Steril</addtitle><date>2009-12-01</date><risdate>2009</risdate><volume>92</volume><issue>6</issue><spage>2047</spage><epage>2049</epage><pages>2047-2049</pages><issn>0015-0282</issn><eissn>1556-5653</eissn><coden>FESTAS</coden><abstract>In this prospective, randomized study, waiting for the lead follicle to reach 14 mm before initiating GnRH antagonist administration effectively prevents an LH surge and ovulation during an IVF cycle. 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source | MEDLINE; Elsevier ScienceDirect Journals; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
subjects | Adult Biological and medical sciences Birth Rate Embryo Implantation Female Fertilization in Vitro - methods Gonadotropin-Releasing Hormone - antagonists & inhibitors Gynecology. Andrology. Obstetrics Humans Infant, Newborn Internal Medicine Luteinizing Hormone - metabolism Medical sciences Obstetrics and Gynecology Ovarian Follicle - anatomy & histology Ovarian Hyperstimulation Syndrome - prevention & control Ovulation - drug effects Pregnancy Pregnancy Outcome Prospective Studies Time Factors |
title | The use of lead follicle diameter to initiate gonadotropin-releasing hormone antagonist does not affect in vitro fertilization clinical pregnancy, implantation, or live birth rates: a prospective, randomized study |
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