The use of lead follicle diameter to initiate gonadotropin-releasing hormone antagonist does not affect in vitro fertilization clinical pregnancy, implantation, or live birth rates: a prospective, randomized study

In this prospective, randomized study, waiting for the lead follicle to reach 14 mm before initiating GnRH antagonist administration effectively prevents an LH surge and ovulation during an IVF cycle. Furthermore, delaying GnRH start until the dominant follicle reaches 14 mm neither impacts the clin...

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Veröffentlicht in:Fertility and sterility 2009-12, Vol.92 (6), p.2047-2049
Hauptverfasser: Dayal, Molina B., M.D., M.P.H, Frankfurter, David, M.D, O'Hern, Candice, M.D, Peak, Douglas, B.S, Dubey, Anil, Ph.D, Gindoff, Paul R., M.D
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container_end_page 2049
container_issue 6
container_start_page 2047
container_title Fertility and sterility
container_volume 92
creator Dayal, Molina B., M.D., M.P.H
Frankfurter, David, M.D
O'Hern, Candice, M.D
Peak, Douglas, B.S
Dubey, Anil, Ph.D
Gindoff, Paul R., M.D
description In this prospective, randomized study, waiting for the lead follicle to reach 14 mm before initiating GnRH antagonist administration effectively prevents an LH surge and ovulation during an IVF cycle. Furthermore, delaying GnRH start until the dominant follicle reaches 14 mm neither impacts the clinical pregnancy, implantation, or live birth rates nor increases the incidence of severe ovarian hyperstimulation syndrome.
doi_str_mv 10.1016/j.fertnstert.2009.05.083
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source MEDLINE; Elsevier ScienceDirect Journals; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects Adult
Biological and medical sciences
Birth Rate
Embryo Implantation
Female
Fertilization in Vitro - methods
Gonadotropin-Releasing Hormone - antagonists & inhibitors
Gynecology. Andrology. Obstetrics
Humans
Infant, Newborn
Internal Medicine
Luteinizing Hormone - metabolism
Medical sciences
Obstetrics and Gynecology
Ovarian Follicle - anatomy & histology
Ovarian Hyperstimulation Syndrome - prevention & control
Ovulation - drug effects
Pregnancy
Pregnancy Outcome
Prospective Studies
Time Factors
title The use of lead follicle diameter to initiate gonadotropin-releasing hormone antagonist does not affect in vitro fertilization clinical pregnancy, implantation, or live birth rates: a prospective, randomized study
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