Structural Analysis of Yoked Chorionic Gonadotropin-Luteinizing Hormone Receptor Ectodomain Complexes by Circular Dichroic Spectroscopy

Binding of the heterodimeric glycoprotein hormone, chorionic gonadotropin (CG), occurs to the heptahelical LH receptor N-terminal ectodomain (ECD), a large portion of which has been modeled as a leucine-rich repeat protein. In this study, we expressed and purified three single chain N-CG-ECD-C compl...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular endocrinology (Baltimore, Md.) Md.), 2003-07, Vol.17 (7), p.1192-1202
Hauptverfasser:	Fralish, Gregory B, Dattilo, Brian, Puett, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites Chorionic Gonadotropin - chemistry Chorionic Gonadotropin - genetics Chorionic Gonadotropin - metabolism Chromatography, Affinity Circular Dichroism Factor Xa - metabolism Glycosylation Humans Insecta - genetics Macromolecular Substances Models, Molecular Protein Binding Protein Conformation Protein Structure, Tertiary Receptors, LH - chemistry Receptors, LH - genetics Receptors, LH - metabolism Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!