Selective Imaging of Damaged Bone Structure (Microcracks) Using a Targeting Supramolecular Eu(III) Complex As a Lanthanide Luminescent Contrast Agent

The synthesis and photophysical evaluation of a new supramolecular lanthanide complex is described which was developed as a luminescent contrast agent for bone structure analysis. We show that the Eu(III) emission of this complex is not pH dependent within the physiological pH range and its steady s...

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Veröffentlicht in:	Journal of the American Chemical Society 2009-12, Vol.131 (48), p.17542-17543
Hauptverfasser:	McMahon, Brian, Mauer, Peter, McCoy, Colin P, Lee, T. Clive, Gunnlaugsson, Thorfinnur
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone and Bones - metabolism Bone and Bones - pathology Calcium - metabolism Cattle Contrast Media - chemistry Contrast Media - metabolism Durapatite - metabolism Europium - chemistry Humans Hydrogen-Ion Concentration Imino Acids - chemistry Lanthanoid Series Elements - chemistry Luminescent Agents - chemistry Luminescent Agents - metabolism Microscopy, Confocal Molecular Imaging - methods Organometallic Compounds - chemistry Organometallic Compounds - metabolism
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