Hydrophilic and hydrophobic amino acid copolymers for nano-comminution of poorly soluble drugs

Nano-comminution has successfully brought nanoparticle formulations of poorly soluble drugs to our daily life. The key for the successful nano-comminution of a drug is the choice of a proper polymeric steric stabilizer. To systematically elucidate the rationale of stabilizer selection, two types of...

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Veröffentlicht in:	International journal of pharmaceutics 2010-01, Vol.384 (1), p.173-180
Hauptverfasser:	Lee, M.K., Kim, S., Ahn, C.-H., Lee, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino Acids - chemistry Amino Acids - genetics Biological and medical sciences Dispersion General pharmacology Hydrophobic and Hydrophilic Interactions Medical sciences Molecular Sequence Data Nanocrystals Nanoparticles Nanoparticles - chemistry Nanotechnology - methods Particle engineering Particle Size Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Polymers - chemistry Poorly water-soluble drug Solubility
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