Ghrelin inhibits post-infarct myocardial remodeling and improves cardiac function through anti-inflammation effect

Ghrelin is a novel growth hormone-releasing peptide, which has been shown to exert beneficial cardiac effects on chronic heart failure (CHF) recently. In this study, we attempted to investigate the mechanisms for the effect of ghrelin on ventricular remodeling following acute myocardial infarction (...

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Veröffentlicht in:	Peptides (New York, N.Y. : 1980) N.Y. : 1980), 2009-12, Vol.30 (12), p.2286-2291
Hauptverfasser:	Huang, Cong-Xin, Yuan, Ming-Jie, Huang, He, Wu, Gang, Liu, Yu, Yu, Sheng-Bo, Li, Hai-Tao, Wang, Tao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Biological and medical sciences Blotting, Western Cardiology. Vascular system Coronary heart disease Enzyme-Linked Immunosorbent Assay Fundamental and applied biological sciences. Psychology Ghrelin Ghrelin - pharmacology Heart In Situ Nick-End Labeling Interleukin-1beta - genetics Interleukin-1beta - metabolism Male Matrix metalloproteinase Matrix Metalloproteinase 2 - genetics Matrix Metalloproteinase 2 - metabolism Matrix Metalloproteinase 9 - genetics Matrix Metalloproteinase 9 - metabolism Medical sciences Myocardial infarction Myocardial Infarction - immunology Myocarditis. Cardiomyopathies Polymerase Chain Reaction Pro-inflammatory cytokines Rats Rats, Sprague-Dawley Tumor Necrosis Factor-alpha - genetics Tumor Necrosis Factor-alpha - metabolism Ventricular Remodeling - drug effects Vertebrates: endocrinology
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