Development and analytical performance evaluation of an automated chemiluminescent immunoassay for pro-gastrin releasing peptide (ProGRP)

Background: Pro-gastrin releasing peptide (ProGRP) concentrations in blood play an important role in the diagnosis and treatment of patients with small cell lung cancer (SCLC). The automated quantitative ARCHITECT® ProGRP assay was developed to aid in the differential diagnosis and in the management...

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Veröffentlicht in:	Clinical chemistry and laboratory medicine 2009, Vol.47 (12), p.1557-1563
Hauptverfasser:	Yoshimura, Toru, Fujita, Kenju, Kinukawa, Hideki, Matsuoka, Yoshiharu, Patil, Rahul D., Beligere, Gangamani S., Chan, Sabrina S., Dowell, Barry L., Sokoll, Lori, Elliott, Debra, Chan, Daniel W., Scheuer, Cornelia, Hofmann, Karin, Stieber, Petra, Sakurai, Yousuke, Iizuka, Masayuki, Saegusa, Haruhisa, Yamaguchi, Ken
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - immunology automated immunoassay Carcinoma, Small Cell - blood Carcinoma, Small Cell - diagnosis Carcinoma, Small Cell - therapy chemiluminescent microparticle immunoassay Humans Immunoassay - methods Immunoassay - standards Luminescence Lung Neoplasms - blood Lung Neoplasms - diagnosis Lung Neoplasms - therapy Peptide Fragments - blood Peptide Fragments - immunology pro-gastrin releasing peptide Recombinant Proteins - blood Recombinant Proteins - immunology Reproducibility of Results Sensitivity and Specificity small cell lung cancer tumor marker
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