The Solution Structure and Self-Association Properties of the Cyclic Lipodepsipeptide Pseudodesmin A Support Its Pore-Forming Potential

Pseudodesmin A is a cyclic lipodepsipeptide (CLP) of the viscosin group with a moderate in vitro biological activity. For several CLPs, including members of this group, this activity has been related to the ability to form ion pores in cellular membranes. As their size does not allow individual CLPs...

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Veröffentlicht in:Chemistry : a European journal 2009-11, Vol.15 (46), p.12653-12662
Hauptverfasser: Sinnaeve, Davy, Hendrickx, Pieter M. S., Van hemel, Johan, Peys, Eric, Kieffer, Bruno, Martins, José C.
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Sprache:eng
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