The diagnostic value of abdominal ultrasound, urine cytology and prostate-specific antigen testing in the lower urinary tract symptoms clinic
Summary Introduction: Lower urinary tract symptoms (LUTS) affect 18–26% of men aged 40–79 years, many of whom present with a fear of having cancer. Current guidelines for the assessment of LUTS focus mainly upon benign prostatic hypertrophy. It has been our practice to perform an abdominal ultrasou...
Gespeichert in:
| Veröffentlicht in: | International journal of clinical practice (Esher) 2009-12, Vol.63 (12), p.1734-1738 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1738 |
|---|---|
| container_issue | 12 |
| container_start_page | 1734 |
| container_title | International journal of clinical practice (Esher) |
| container_volume | 63 |
| creator | Patel, N. S. Blick, C. Kumar, P. V. S. Malone, P. R. |
| description | Summary
Introduction: Lower urinary tract symptoms (LUTS) affect 18–26% of men aged 40–79 years, many of whom present with a fear of having cancer. Current guidelines for the assessment of LUTS focus mainly upon benign prostatic hypertrophy. It has been our practice to perform an abdominal ultrasound scan (USS), a prostate‐specific antigen (PSA) blood test and urine cytology during the assessment of males presenting with LUTS to investigate the alternative potentially life‐threatening causes for LUTS. We report on the added value of these tests during the assessment of men with LUTS.
Results: A total of 263/3976 (6.6%) patients investigated for LUTS were found to have incidental urological malignancies, urinary tract calculi or abdominal aortic aneurysms (AAA). Abdominal USSs resulted in the incidental diagnosis of four renal carcinomas (0.1%), 45 AAAs (incidence = 1.1%) and 44 urinary tract calculi (1.1%). Urine cytology testing and bladder USSs helped diagnose 17 new bladder cancers (0.4%), five of which did not present with haematuria. Patients found to have an elevated age‐specific PSA had a 23.6% chance of being diagnosed with prostate cancer (3.8%).
Conclusion: The addition of abdominal ultrasound scanning, urine cytology and PSA testing as part of an LUTS assessment protocol can help to diagnose significant, potentially life‐threatening conditions in up to 6.6% of patients. While the pick up rate of each individual condition is not higher in the LUTS patient than in the general population, the combined pick up rate may justify these additional investigations. |
| doi_str_mv | 10.1111/j.1742-1241.2009.02138.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_734151549</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>734151549</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5148-6cda635d39b3eb2486b03935e253481fd8a1b31dfc9e425ec9c4763d93ece3fb3</originalsourceid><addsrcrecordid>eNqNkc-O0zAQhyMEYpeFV0AWEuKyKbbHTuILEir7VxVwWMTRcpxJcXGcbpyw7UPwzrjbqkic8MUj-ZvPY_-yjDA6Y2m9X81YKXjOuGAzTqmaUc6gmm2eZKfHg6ephqLKJQV2kr2IcUUpl7Kiz7MTphRQAHGa_b77gaRxZhn6ODpLfhk_IelbYuqm71wwnkx-HEzsp9Cck2lwAYndjr3vl1tiQkPWQ-o0I-Zxjda1yWHC6JYYyIhJGZbEpTLd4vsHHB4NZtiS5LQjidtuPfZdJNa74OzL7FlrfMRXh_0s-3Z5cTe_zhdfrm7mHxe5lUxUeWEbU4BsQNWANRdVUVNQIJFLEBVrm8qwGljTWoWCS7TKirKARgFahLaGs-zd3puGv5_SmLpz0aL3JmA_RV2CYJJJoRL55h9y1U9D-paoOVeKgpQiQdUesukv4oCtXg-uS6_UjOpdYHqld7noXS56F5h-DExvUuvrg3-qO2z-Nh4SSsDbA2CiNb4dTLAuHjnOWXp0wRP3Yc89OI_b_x5A39zOv-7KJMj3AhdH3BwFZvipixJKqb9_vtK380v2iV6XegF_ACa7wt4</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>229903554</pqid></control><display><type>article</type><title>The diagnostic value of abdominal ultrasound, urine cytology and prostate-specific antigen testing in the lower urinary tract symptoms clinic</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Patel, N. S. ; Blick, C. ; Kumar, P. V. S. ; Malone, P. R.</creator><creatorcontrib>Patel, N. S. ; Blick, C. ; Kumar, P. V. S. ; Malone, P. R.</creatorcontrib><description>Summary
Introduction: Lower urinary tract symptoms (LUTS) affect 18–26% of men aged 40–79 years, many of whom present with a fear of having cancer. Current guidelines for the assessment of LUTS focus mainly upon benign prostatic hypertrophy. It has been our practice to perform an abdominal ultrasound scan (USS), a prostate‐specific antigen (PSA) blood test and urine cytology during the assessment of males presenting with LUTS to investigate the alternative potentially life‐threatening causes for LUTS. We report on the added value of these tests during the assessment of men with LUTS.
Results: A total of 263/3976 (6.6%) patients investigated for LUTS were found to have incidental urological malignancies, urinary tract calculi or abdominal aortic aneurysms (AAA). Abdominal USSs resulted in the incidental diagnosis of four renal carcinomas (0.1%), 45 AAAs (incidence = 1.1%) and 44 urinary tract calculi (1.1%). Urine cytology testing and bladder USSs helped diagnose 17 new bladder cancers (0.4%), five of which did not present with haematuria. Patients found to have an elevated age‐specific PSA had a 23.6% chance of being diagnosed with prostate cancer (3.8%).
Conclusion: The addition of abdominal ultrasound scanning, urine cytology and PSA testing as part of an LUTS assessment protocol can help to diagnose significant, potentially life‐threatening conditions in up to 6.6% of patients. While the pick up rate of each individual condition is not higher in the LUTS patient than in the general population, the combined pick up rate may justify these additional investigations.</description><identifier>ISSN: 1368-5031</identifier><identifier>EISSN: 1742-1241</identifier><identifier>DOI: 10.1111/j.1742-1241.2009.02138.x</identifier><identifier>PMID: 19930334</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adolescent ; Adrenal Gland Neoplasms - diagnostic imaging ; Adult ; Aged ; Aged, 80 and over ; Aortic Aneurysm, Abdominal - diagnostic imaging ; Biological and medical sciences ; Carcinoma, Renal Cell - diagnostic imaging ; Carcinoma, Transitional Cell - pathology ; Diagnostic tests ; General aspects ; Humans ; Hydronephrosis - diagnostic imaging ; Incidental Findings ; Kidney Neoplasms - urine ; Male ; Medical diagnosis ; Medical sciences ; Mens health ; Middle Aged ; Nephrology. Urinary tract diseases ; Prevention and actions ; Prostate-Specific Antigen - blood ; Prostatic Hyperplasia - pathology ; Prostatic Neoplasms - pathology ; Prostatism - diagnosis ; Prostatism - etiology ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Ultrasonic imaging ; Ultrasonography ; Urinary Bladder Neoplasms - pathology ; Urinary Calculi - diagnostic imaging ; Urinary system involvement in other diseases. Miscellaneous ; Urinary tract. Prostate gland ; Urine - cytology ; Urology ; Young Adult</subject><ispartof>International journal of clinical practice (Esher), 2009-12, Vol.63 (12), p.1734-1738</ispartof><rights>2009 Blackwell Publishing Ltd</rights><rights>2009 INIST-CNRS</rights><rights>Journal compilation © 2009 Blackwell Publishing Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5148-6cda635d39b3eb2486b03935e253481fd8a1b31dfc9e425ec9c4763d93ece3fb3</citedby><cites>FETCH-LOGICAL-c5148-6cda635d39b3eb2486b03935e253481fd8a1b31dfc9e425ec9c4763d93ece3fb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1742-1241.2009.02138.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1742-1241.2009.02138.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22125362$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19930334$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Patel, N. S.</creatorcontrib><creatorcontrib>Blick, C.</creatorcontrib><creatorcontrib>Kumar, P. V. S.</creatorcontrib><creatorcontrib>Malone, P. R.</creatorcontrib><title>The diagnostic value of abdominal ultrasound, urine cytology and prostate-specific antigen testing in the lower urinary tract symptoms clinic</title><title>International journal of clinical practice (Esher)</title><addtitle>Int J Clin Pract</addtitle><description>Summary
Introduction: Lower urinary tract symptoms (LUTS) affect 18–26% of men aged 40–79 years, many of whom present with a fear of having cancer. Current guidelines for the assessment of LUTS focus mainly upon benign prostatic hypertrophy. It has been our practice to perform an abdominal ultrasound scan (USS), a prostate‐specific antigen (PSA) blood test and urine cytology during the assessment of males presenting with LUTS to investigate the alternative potentially life‐threatening causes for LUTS. We report on the added value of these tests during the assessment of men with LUTS.
Results: A total of 263/3976 (6.6%) patients investigated for LUTS were found to have incidental urological malignancies, urinary tract calculi or abdominal aortic aneurysms (AAA). Abdominal USSs resulted in the incidental diagnosis of four renal carcinomas (0.1%), 45 AAAs (incidence = 1.1%) and 44 urinary tract calculi (1.1%). Urine cytology testing and bladder USSs helped diagnose 17 new bladder cancers (0.4%), five of which did not present with haematuria. Patients found to have an elevated age‐specific PSA had a 23.6% chance of being diagnosed with prostate cancer (3.8%).
Conclusion: The addition of abdominal ultrasound scanning, urine cytology and PSA testing as part of an LUTS assessment protocol can help to diagnose significant, potentially life‐threatening conditions in up to 6.6% of patients. While the pick up rate of each individual condition is not higher in the LUTS patient than in the general population, the combined pick up rate may justify these additional investigations.</description><subject>Adolescent</subject><subject>Adrenal Gland Neoplasms - diagnostic imaging</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aortic Aneurysm, Abdominal - diagnostic imaging</subject><subject>Biological and medical sciences</subject><subject>Carcinoma, Renal Cell - diagnostic imaging</subject><subject>Carcinoma, Transitional Cell - pathology</subject><subject>Diagnostic tests</subject><subject>General aspects</subject><subject>Humans</subject><subject>Hydronephrosis - diagnostic imaging</subject><subject>Incidental Findings</subject><subject>Kidney Neoplasms - urine</subject><subject>Male</subject><subject>Medical diagnosis</subject><subject>Medical sciences</subject><subject>Mens health</subject><subject>Middle Aged</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Prevention and actions</subject><subject>Prostate-Specific Antigen - blood</subject><subject>Prostatic Hyperplasia - pathology</subject><subject>Prostatic Neoplasms - pathology</subject><subject>Prostatism - diagnosis</subject><subject>Prostatism - etiology</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Ultrasonic imaging</subject><subject>Ultrasonography</subject><subject>Urinary Bladder Neoplasms - pathology</subject><subject>Urinary Calculi - diagnostic imaging</subject><subject>Urinary system involvement in other diseases. Miscellaneous</subject><subject>Urinary tract. Prostate gland</subject><subject>Urine - cytology</subject><subject>Urology</subject><subject>Young Adult</subject><issn>1368-5031</issn><issn>1742-1241</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkc-O0zAQhyMEYpeFV0AWEuKyKbbHTuILEir7VxVwWMTRcpxJcXGcbpyw7UPwzrjbqkic8MUj-ZvPY_-yjDA6Y2m9X81YKXjOuGAzTqmaUc6gmm2eZKfHg6ephqLKJQV2kr2IcUUpl7Kiz7MTphRQAHGa_b77gaRxZhn6ODpLfhk_IelbYuqm71wwnkx-HEzsp9Cck2lwAYndjr3vl1tiQkPWQ-o0I-Zxjda1yWHC6JYYyIhJGZbEpTLd4vsHHB4NZtiS5LQjidtuPfZdJNa74OzL7FlrfMRXh_0s-3Z5cTe_zhdfrm7mHxe5lUxUeWEbU4BsQNWANRdVUVNQIJFLEBVrm8qwGljTWoWCS7TKirKARgFahLaGs-zd3puGv5_SmLpz0aL3JmA_RV2CYJJJoRL55h9y1U9D-paoOVeKgpQiQdUesukv4oCtXg-uS6_UjOpdYHqld7noXS56F5h-DExvUuvrg3-qO2z-Nh4SSsDbA2CiNb4dTLAuHjnOWXp0wRP3Yc89OI_b_x5A39zOv-7KJMj3AhdH3BwFZvipixJKqb9_vtK380v2iV6XegF_ACa7wt4</recordid><startdate>200912</startdate><enddate>200912</enddate><creator>Patel, N. S.</creator><creator>Blick, C.</creator><creator>Kumar, P. V. S.</creator><creator>Malone, P. R.</creator><general>Blackwell Publishing Ltd</general><general>Wiley-Blackwell</general><general>Hindawi Limited</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7T5</scope><scope>7TK</scope><scope>7TS</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>200912</creationdate><title>The diagnostic value of abdominal ultrasound, urine cytology and prostate-specific antigen testing in the lower urinary tract symptoms clinic</title><author>Patel, N. S. ; Blick, C. ; Kumar, P. V. S. ; Malone, P. R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5148-6cda635d39b3eb2486b03935e253481fd8a1b31dfc9e425ec9c4763d93ece3fb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adolescent</topic><topic>Adrenal Gland Neoplasms - diagnostic imaging</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aortic Aneurysm, Abdominal - diagnostic imaging</topic><topic>Biological and medical sciences</topic><topic>Carcinoma, Renal Cell - diagnostic imaging</topic><topic>Carcinoma, Transitional Cell - pathology</topic><topic>Diagnostic tests</topic><topic>General aspects</topic><topic>Humans</topic><topic>Hydronephrosis - diagnostic imaging</topic><topic>Incidental Findings</topic><topic>Kidney Neoplasms - urine</topic><topic>Male</topic><topic>Medical diagnosis</topic><topic>Medical sciences</topic><topic>Mens health</topic><topic>Middle Aged</topic><topic>Nephrology. Urinary tract diseases</topic><topic>Prevention and actions</topic><topic>Prostate-Specific Antigen - blood</topic><topic>Prostatic Hyperplasia - pathology</topic><topic>Prostatic Neoplasms - pathology</topic><topic>Prostatism - diagnosis</topic><topic>Prostatism - etiology</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Ultrasonic imaging</topic><topic>Ultrasonography</topic><topic>Urinary Bladder Neoplasms - pathology</topic><topic>Urinary Calculi - diagnostic imaging</topic><topic>Urinary system involvement in other diseases. Miscellaneous</topic><topic>Urinary tract. Prostate gland</topic><topic>Urine - cytology</topic><topic>Urology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Patel, N. S.</creatorcontrib><creatorcontrib>Blick, C.</creatorcontrib><creatorcontrib>Kumar, P. V. S.</creatorcontrib><creatorcontrib>Malone, P. R.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Physical Education Index</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of clinical practice (Esher)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Patel, N. S.</au><au>Blick, C.</au><au>Kumar, P. V. S.</au><au>Malone, P. R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The diagnostic value of abdominal ultrasound, urine cytology and prostate-specific antigen testing in the lower urinary tract symptoms clinic</atitle><jtitle>International journal of clinical practice (Esher)</jtitle><addtitle>Int J Clin Pract</addtitle><date>2009-12</date><risdate>2009</risdate><volume>63</volume><issue>12</issue><spage>1734</spage><epage>1738</epage><pages>1734-1738</pages><issn>1368-5031</issn><eissn>1742-1241</eissn><abstract>Summary
Introduction: Lower urinary tract symptoms (LUTS) affect 18–26% of men aged 40–79 years, many of whom present with a fear of having cancer. Current guidelines for the assessment of LUTS focus mainly upon benign prostatic hypertrophy. It has been our practice to perform an abdominal ultrasound scan (USS), a prostate‐specific antigen (PSA) blood test and urine cytology during the assessment of males presenting with LUTS to investigate the alternative potentially life‐threatening causes for LUTS. We report on the added value of these tests during the assessment of men with LUTS.
Results: A total of 263/3976 (6.6%) patients investigated for LUTS were found to have incidental urological malignancies, urinary tract calculi or abdominal aortic aneurysms (AAA). Abdominal USSs resulted in the incidental diagnosis of four renal carcinomas (0.1%), 45 AAAs (incidence = 1.1%) and 44 urinary tract calculi (1.1%). Urine cytology testing and bladder USSs helped diagnose 17 new bladder cancers (0.4%), five of which did not present with haematuria. Patients found to have an elevated age‐specific PSA had a 23.6% chance of being diagnosed with prostate cancer (3.8%).
Conclusion: The addition of abdominal ultrasound scanning, urine cytology and PSA testing as part of an LUTS assessment protocol can help to diagnose significant, potentially life‐threatening conditions in up to 6.6% of patients. While the pick up rate of each individual condition is not higher in the LUTS patient than in the general population, the combined pick up rate may justify these additional investigations.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>19930334</pmid><doi>10.1111/j.1742-1241.2009.02138.x</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1368-5031 |
| ispartof | International journal of clinical practice (Esher), 2009-12, Vol.63 (12), p.1734-1738 |
| issn | 1368-5031 1742-1241 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_734151549 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adolescent Adrenal Gland Neoplasms - diagnostic imaging Adult Aged Aged, 80 and over Aortic Aneurysm, Abdominal - diagnostic imaging Biological and medical sciences Carcinoma, Renal Cell - diagnostic imaging Carcinoma, Transitional Cell - pathology Diagnostic tests General aspects Humans Hydronephrosis - diagnostic imaging Incidental Findings Kidney Neoplasms - urine Male Medical diagnosis Medical sciences Mens health Middle Aged Nephrology. Urinary tract diseases Prevention and actions Prostate-Specific Antigen - blood Prostatic Hyperplasia - pathology Prostatic Neoplasms - pathology Prostatism - diagnosis Prostatism - etiology Public health. Hygiene Public health. Hygiene-occupational medicine Ultrasonic imaging Ultrasonography Urinary Bladder Neoplasms - pathology Urinary Calculi - diagnostic imaging Urinary system involvement in other diseases. Miscellaneous Urinary tract. Prostate gland Urine - cytology Urology Young Adult |
| title | The diagnostic value of abdominal ultrasound, urine cytology and prostate-specific antigen testing in the lower urinary tract symptoms clinic |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T16%3A18%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20diagnostic%20value%20of%20abdominal%20ultrasound,%20urine%20cytology%20and%20prostate-specific%20antigen%20testing%20in%20the%20lower%20urinary%20tract%20symptoms%20clinic&rft.jtitle=International%20journal%20of%20clinical%20practice%20(Esher)&rft.au=Patel,%20N.%20S.&rft.date=2009-12&rft.volume=63&rft.issue=12&rft.spage=1734&rft.epage=1738&rft.pages=1734-1738&rft.issn=1368-5031&rft.eissn=1742-1241&rft_id=info:doi/10.1111/j.1742-1241.2009.02138.x&rft_dat=%3Cproquest_cross%3E734151549%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=229903554&rft_id=info:pmid/19930334&rfr_iscdi=true |