Significance of Neonatal Testicular Sex Steroids to Defeminize Anteroventral Periventricular Kisspeptin Neurons and the GnRH/LH Surge System in Male Rats

The brain mechanism regulating gonadotropin-releasing hormone (GnRH)/luteinizing hormone (LH) release is sexually differentiated in rodents. Kisspeptin neurons in the anteroventral periventricular nucleus (AVPV) have been suggested to be sexually dimorphic and involved in the GnRH/LH surge generatio...

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Veröffentlicht in:	Biology of reproduction 2009-12, Vol.81 (6), p.1216-1225
Hauptverfasser:	Homma, Tamami, Sakakibara, Mototsugu, Yamada, Shunji, Kinoshita, Mika, Iwata, Kinuyo, Tomikawa, Junko, Kanazawa, Tetsuhiro, Matsui, Hisanori, Takatsu, Yoshihiro, Ohtaki, Tetsuya, Matsumoto, Hirokazu, Uenoyama, Yoshihisa, Maeda, Kei-ichiro, Tsukamura, Hiroko
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Androgens - metabolism Animals Animals, Newborn Cell Count Dopamine - genetics Dopamine - metabolism Estradiol - metabolism Estradiol - pharmacology Female Galanin - genetics Galanin - metabolism gamma-Aminobutyric Acid - genetics gamma-Aminobutyric Acid - metabolism Gene Expression Regulation, Developmental - drug effects Glutamic Acid - genetics Glutamic Acid - metabolism Gonadotropin-Releasing Hormone - metabolism Hypothalamo-Hypophyseal System - drug effects Hypothalamo-Hypophyseal System - growth & development Hypothalamo-Hypophyseal System - metabolism Hypothalamus - drug effects Hypothalamus - growth & development Hypothalamus - metabolism Immunohistochemistry In Situ Hybridization Kisspeptins Luteinizing Hormone - metabolism Male Neurons - metabolism Neurotensin - genetics Neurotensin - metabolism Orchiectomy Ovariectomy Proteins - genetics Proteins - metabolism Rats Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - drug effects RNA, Messenger - genetics RNA, Messenger - metabolism Sex Differentiation - physiology
Online-Zugang:	Volltext
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