Effects of curcumin for preventing restenosis in a hypercholesterolemic rabbit iliac artery stent model

Objective: To evaluate the efficacy of the curcumin‐coating stent (CCS) on the inhibition of restenosis in a rabbit iliac artery stent model. Results: Curcumin, pigment naturally acquired from the rhizome of the plant curcuma longa, is known to have antiproliferative, antimigratory, and anti‐inflamm...

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Veröffentlicht in:	Catheterization and cardiovascular interventions 2009-11, Vol.74 (6), p.881-888
Hauptverfasser:	Jang, Hyung-Suk, Nam, Hye Yeong, Kim, Jeong-Min, Hahm, Dong-Hoon, Nam, So Hee, Kim, Koung Li, Joo, Jae-Ryang, Suh, Wonhee, Park, Jong-Sang, Kim, Duk Kyung, Gwon, Hyeon-Cheol
Format:	Artikel
Sprache:	eng
Schlagworte:	Angioplasty, Balloon - adverse effects Angioplasty, Balloon - instrumentation Animals Arterial Occlusive Diseases - etiology Arterial Occlusive Diseases - pathology Arterial Occlusive Diseases - prevention & control Cardiovascular Agents - administration & dosage Cell Movement - drug effects Cell Proliferation - drug effects Cells, Cultured Coated Materials, Biocompatible Constriction, Pathologic curcumin Curcumin - administration & dosage Disease Models, Animal Dose-Response Relationship, Drug drug-eluting stent Drug-Eluting Stents - adverse effects Hypercholesterolemia - complications Iliac Artery - drug effects Iliac Artery - pathology Male Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - metabolism Muscle, Smooth, Vascular - pathology Myocytes, Smooth Muscle - drug effects Myocytes, Smooth Muscle - metabolism Myocytes, Smooth Muscle - pathology Platelet-Derived Growth Factor - metabolism Prosthesis Design Proto-Oncogene Proteins c-sis Rabbits Rats Rats, Sprague-Dawley restenosis Surface Properties Time Factors
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