Death After Colectomy: It's Later Than We Think

BACKGROUND Clinical outcomes are increasingly subject to objective assessment and professional accountability. Informed consent relies on accurate estimation of operative risk. Current scoring systems for assessment of operative mortality after colorectal surgery (CRS) almost uniformly report 30-day...

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Veröffentlicht in:Archives of surgery (Chicago. 1960) 2009-11, Vol.144 (11), p.1021-1027
Hauptverfasser: Visser, Brendan C, Keegan, Hugh, Martin, Molinda, Wren, Sherry M
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container_end_page 1027
container_issue 11
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container_title Archives of surgery (Chicago. 1960)
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creator Visser, Brendan C
Keegan, Hugh
Martin, Molinda
Wren, Sherry M
description BACKGROUND Clinical outcomes are increasingly subject to objective assessment and professional accountability. Informed consent relies on accurate estimation of operative risk. Current scoring systems for assessment of operative mortality after colorectal surgery (CRS) almost uniformly report 30-day mortality and may not represent true risk. DESIGN Prospective cohort. SETTING University-affiliated Veterans Affairs Medical Center. PATIENTS All patients who underwent resections of the colon and/or rectum (as the principal operation) at a single hospital whose data are captured in the Veterans Affairs National Surgical Quality Improvement Program (VA-NSQIP) database from January 1, 2000, through December 31, 2006. MAIN OUTCOME MEASURES Mortality at 30 days and 90 days. RESULTS The VA-NSQIP cohort included 186 patients who underwent CRS, including 148 patients who underwent elective procedures (79.6%) and 38 patients who underwent emergency procedures (20.4%). All but 8 patients were men, with a median age of 67 years (range, 26-92 years). Laparoscopic operations comprised 24.2% and open operations comprised 75.8%. Most (60.8%) were performed for neoplasms. The actual 30-day mortality rates (all, elective, and emergency procedures) were 4.3%, 1.4%, and 15.8%, respectively. These rates closely mirrored the calculated VA-NSQIP risk-adjusted observed-to-expected ratio for 30-day mortality (4.8%, 1.8%, and 18.2%, respectively). However, mortality at 90 days increased substantially to 9.1%, 4.1%, and 28.9%, respectively. CONCLUSION The 30-day mortality significantly underreports the true risk of death after CRS. The 90-day mortality rate should be included as a standard outcome measure after CRS because it serves as a better estimation of risk for counseling patients.Arch Surg. 2009;144(11):1021-1027-->
doi_str_mv 10.1001/archsurg.2009.197
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Informed consent relies on accurate estimation of operative risk. Current scoring systems for assessment of operative mortality after colorectal surgery (CRS) almost uniformly report 30-day mortality and may not represent true risk. DESIGN Prospective cohort. SETTING University-affiliated Veterans Affairs Medical Center. PATIENTS All patients who underwent resections of the colon and/or rectum (as the principal operation) at a single hospital whose data are captured in the Veterans Affairs National Surgical Quality Improvement Program (VA-NSQIP) database from January 1, 2000, through December 31, 2006. MAIN OUTCOME MEASURES Mortality at 30 days and 90 days. RESULTS The VA-NSQIP cohort included 186 patients who underwent CRS, including 148 patients who underwent elective procedures (79.6%) and 38 patients who underwent emergency procedures (20.4%). All but 8 patients were men, with a median age of 67 years (range, 26-92 years). Laparoscopic operations comprised 24.2% and open operations comprised 75.8%. Most (60.8%) were performed for neoplasms. The actual 30-day mortality rates (all, elective, and emergency procedures) were 4.3%, 1.4%, and 15.8%, respectively. These rates closely mirrored the calculated VA-NSQIP risk-adjusted observed-to-expected ratio for 30-day mortality (4.8%, 1.8%, and 18.2%, respectively). However, mortality at 90 days increased substantially to 9.1%, 4.1%, and 28.9%, respectively. CONCLUSION The 30-day mortality significantly underreports the true risk of death after CRS. The 90-day mortality rate should be included as a standard outcome measure after CRS because it serves as a better estimation of risk for counseling patients.Arch Surg. 2009;144(11):1021-1027--&gt;</description><identifier>ISSN: 0004-0010</identifier><identifier>ISSN: 2168-6254</identifier><identifier>EISSN: 1538-3644</identifier><identifier>EISSN: 2168-6262</identifier><identifier>DOI: 10.1001/archsurg.2009.197</identifier><identifier>PMID: 19917938</identifier><identifier>CODEN: ARSUAX</identifier><language>eng</language><publisher>Chicago, IL: American Medical Association</publisher><subject>Academic Medical Centers ; Age Distribution ; Biological and medical sciences ; California ; Cause of Death ; Clinical outcomes ; Cohort Studies ; Colectomy - methods ; Colectomy - mortality ; Colonoscopy - methods ; Colonoscopy - mortality ; Colorectal Neoplasms - diagnosis ; Colorectal Neoplasms - mortality ; Colorectal Neoplasms - surgery ; Colorectal surgery ; Female ; Follow-Up Studies ; General aspects ; Hospital Mortality - trends ; Hospitals, Veterans ; Humans ; Incidence ; Male ; Medical sciences ; Mortality ; Postoperative Complications - mortality ; Prospective Studies ; Risk Assessment ; Severity of Illness Index ; Sex Distribution ; Stomach, duodenum, intestine, rectum, anus ; Surgery (general aspects). Transplantations, organ and tissue grafts. 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Informed consent relies on accurate estimation of operative risk. Current scoring systems for assessment of operative mortality after colorectal surgery (CRS) almost uniformly report 30-day mortality and may not represent true risk. DESIGN Prospective cohort. SETTING University-affiliated Veterans Affairs Medical Center. PATIENTS All patients who underwent resections of the colon and/or rectum (as the principal operation) at a single hospital whose data are captured in the Veterans Affairs National Surgical Quality Improvement Program (VA-NSQIP) database from January 1, 2000, through December 31, 2006. MAIN OUTCOME MEASURES Mortality at 30 days and 90 days. RESULTS The VA-NSQIP cohort included 186 patients who underwent CRS, including 148 patients who underwent elective procedures (79.6%) and 38 patients who underwent emergency procedures (20.4%). All but 8 patients were men, with a median age of 67 years (range, 26-92 years). Laparoscopic operations comprised 24.2% and open operations comprised 75.8%. Most (60.8%) were performed for neoplasms. The actual 30-day mortality rates (all, elective, and emergency procedures) were 4.3%, 1.4%, and 15.8%, respectively. These rates closely mirrored the calculated VA-NSQIP risk-adjusted observed-to-expected ratio for 30-day mortality (4.8%, 1.8%, and 18.2%, respectively). However, mortality at 90 days increased substantially to 9.1%, 4.1%, and 28.9%, respectively. CONCLUSION The 30-day mortality significantly underreports the true risk of death after CRS. The 90-day mortality rate should be included as a standard outcome measure after CRS because it serves as a better estimation of risk for counseling patients.Arch Surg. 2009;144(11):1021-1027--&gt;</description><subject>Academic Medical Centers</subject><subject>Age Distribution</subject><subject>Biological and medical sciences</subject><subject>California</subject><subject>Cause of Death</subject><subject>Clinical outcomes</subject><subject>Cohort Studies</subject><subject>Colectomy - methods</subject><subject>Colectomy - mortality</subject><subject>Colonoscopy - methods</subject><subject>Colonoscopy - mortality</subject><subject>Colorectal Neoplasms - diagnosis</subject><subject>Colorectal Neoplasms - mortality</subject><subject>Colorectal Neoplasms - surgery</subject><subject>Colorectal surgery</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>General aspects</subject><subject>Hospital Mortality - trends</subject><subject>Hospitals, Veterans</subject><subject>Humans</subject><subject>Incidence</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mortality</subject><subject>Postoperative Complications - mortality</subject><subject>Prospective Studies</subject><subject>Risk Assessment</subject><subject>Severity of Illness Index</subject><subject>Sex Distribution</subject><subject>Stomach, duodenum, intestine, rectum, anus</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the digestive system</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><issn>0004-0010</issn><issn>2168-6254</issn><issn>1538-3644</issn><issn>2168-6262</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkE1Lw0AQhhdRbK3-gF4kCNJT2v1KN-ut1K9CwUvF4zLZbGxqPupucui_d0NjBU8zzDwzvDwIjQmeEozJDKzeutZ-TinGckqkOENDErE4ZHPOz9EQY8xDD-IBunJu5zsaS3qJBkRKIiSLh2j2aKDZBousMTZY1oXRTV0eHoJVM3HBGrrpZgtV8GF8zauva3SRQeHMTV9H6P35abN8DddvL6vlYh0Co6IJMypMlqY6klwSkIKmIklEmum5gYQak2rOOUtiYNIIgynmc9BSCJphksyxYCM0Of7d2_q7Na5RZe60KQqoTN06JRgnnPGYe_LuH7mrW1v5cIoyGkVUMOIhcoS0rZ2zJlN7m5dgD4pg1blUvy5V51J5l_7mtn_cJqVJ_y56eR647wFwGorMQqVzd-IoxZJFoks4PnJQwmnLccSjiP0Au_6EBQ</recordid><startdate>20091101</startdate><enddate>20091101</enddate><creator>Visser, Brendan C</creator><creator>Keegan, Hugh</creator><creator>Martin, Molinda</creator><creator>Wren, Sherry M</creator><general>American Medical Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20091101</creationdate><title>Death After Colectomy: It's Later Than We Think</title><author>Visser, Brendan C ; Keegan, Hugh ; Martin, Molinda ; Wren, Sherry M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a327t-f27efddc59491a972d7bb7dfc6eab2eedc4443b8a39e7e02046ac9772f01b6073</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Academic Medical Centers</topic><topic>Age Distribution</topic><topic>Biological and medical sciences</topic><topic>California</topic><topic>Cause of Death</topic><topic>Clinical outcomes</topic><topic>Cohort Studies</topic><topic>Colectomy - methods</topic><topic>Colectomy - mortality</topic><topic>Colonoscopy - methods</topic><topic>Colonoscopy - mortality</topic><topic>Colorectal Neoplasms - diagnosis</topic><topic>Colorectal Neoplasms - mortality</topic><topic>Colorectal Neoplasms - surgery</topic><topic>Colorectal surgery</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>General aspects</topic><topic>Hospital Mortality - trends</topic><topic>Hospitals, Veterans</topic><topic>Humans</topic><topic>Incidence</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mortality</topic><topic>Postoperative Complications - mortality</topic><topic>Prospective Studies</topic><topic>Risk Assessment</topic><topic>Severity of Illness Index</topic><topic>Sex Distribution</topic><topic>Stomach, duodenum, intestine, rectum, anus</topic><topic>Surgery (general aspects). 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Graft diseases</topic><topic>Surgery of the digestive system</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><toplevel>online_resources</toplevel><creatorcontrib>Visser, Brendan C</creatorcontrib><creatorcontrib>Keegan, Hugh</creatorcontrib><creatorcontrib>Martin, Molinda</creatorcontrib><creatorcontrib>Wren, Sherry M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of surgery (Chicago. 1960)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Visser, Brendan C</au><au>Keegan, Hugh</au><au>Martin, Molinda</au><au>Wren, Sherry M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Death After Colectomy: It's Later Than We Think</atitle><jtitle>Archives of surgery (Chicago. 1960)</jtitle><addtitle>Arch Surg</addtitle><date>2009-11-01</date><risdate>2009</risdate><volume>144</volume><issue>11</issue><spage>1021</spage><epage>1027</epage><pages>1021-1027</pages><issn>0004-0010</issn><issn>2168-6254</issn><eissn>1538-3644</eissn><eissn>2168-6262</eissn><coden>ARSUAX</coden><abstract>BACKGROUND Clinical outcomes are increasingly subject to objective assessment and professional accountability. Informed consent relies on accurate estimation of operative risk. Current scoring systems for assessment of operative mortality after colorectal surgery (CRS) almost uniformly report 30-day mortality and may not represent true risk. DESIGN Prospective cohort. SETTING University-affiliated Veterans Affairs Medical Center. PATIENTS All patients who underwent resections of the colon and/or rectum (as the principal operation) at a single hospital whose data are captured in the Veterans Affairs National Surgical Quality Improvement Program (VA-NSQIP) database from January 1, 2000, through December 31, 2006. MAIN OUTCOME MEASURES Mortality at 30 days and 90 days. RESULTS The VA-NSQIP cohort included 186 patients who underwent CRS, including 148 patients who underwent elective procedures (79.6%) and 38 patients who underwent emergency procedures (20.4%). All but 8 patients were men, with a median age of 67 years (range, 26-92 years). Laparoscopic operations comprised 24.2% and open operations comprised 75.8%. Most (60.8%) were performed for neoplasms. The actual 30-day mortality rates (all, elective, and emergency procedures) were 4.3%, 1.4%, and 15.8%, respectively. These rates closely mirrored the calculated VA-NSQIP risk-adjusted observed-to-expected ratio for 30-day mortality (4.8%, 1.8%, and 18.2%, respectively). However, mortality at 90 days increased substantially to 9.1%, 4.1%, and 28.9%, respectively. CONCLUSION The 30-day mortality significantly underreports the true risk of death after CRS. The 90-day mortality rate should be included as a standard outcome measure after CRS because it serves as a better estimation of risk for counseling patients.Arch Surg. 2009;144(11):1021-1027--&gt;</abstract><cop>Chicago, IL</cop><pub>American Medical Association</pub><pmid>19917938</pmid><doi>10.1001/archsurg.2009.197</doi><tpages>7</tpages></addata></record>
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subjects Academic Medical Centers
Age Distribution
Biological and medical sciences
California
Cause of Death
Clinical outcomes
Cohort Studies
Colectomy - methods
Colectomy - mortality
Colonoscopy - methods
Colonoscopy - mortality
Colorectal Neoplasms - diagnosis
Colorectal Neoplasms - mortality
Colorectal Neoplasms - surgery
Colorectal surgery
Female
Follow-Up Studies
General aspects
Hospital Mortality - trends
Hospitals, Veterans
Humans
Incidence
Male
Medical sciences
Mortality
Postoperative Complications - mortality
Prospective Studies
Risk Assessment
Severity of Illness Index
Sex Distribution
Stomach, duodenum, intestine, rectum, anus
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the digestive system
Time Factors
Treatment Outcome
title Death After Colectomy: It's Later Than We Think
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