Arsenic trioxide in combination with all-trans retinoic acid for acute promyelocytic leukemia: a systematic review and meta-analysis
The studies have demonstrated that arsenic trioxide (ATO) in combination with all-trans retinoic acid (ATRA) takes effects in treatment of acute promyelocytic leukemia (APL) through different underlying mechanisms. This has established the molecular foundation of ATO plus ATRA therapy. Currently, AT...
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| Veröffentlicht in: | Zhong xi yi jie he xue bao 2009-11, Vol.7 (11), p.1024-1034 |
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| container_issue | 11 |
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| container_title | Zhong xi yi jie he xue bao |
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| creator | Xu, Shuang-nian Chen, Jie-ping Liu, Jian-ping Xia, Yun |
| description | The studies have demonstrated that arsenic trioxide (ATO) in combination with all-trans retinoic acid (ATRA) takes effects in treatment of acute promyelocytic leukemia (APL) through different underlying mechanisms. This has established the molecular foundation of ATO plus ATRA therapy. Currently, ATO plus ATRA has also been widely used in clinical practice.
To assess the efficacy and safety of ATO in combination with ATRA for APL.
The Cochrane Library (Issue 1, 2009), Cochrane Central Register of Controlled Trials (from 1970 to January 2009), MEDLINE (from 1978 to October 2008), EMBASE (from 1950 to March 2009), Chinese Biological Medical Literature Database (from 1978 to December 2008), CNKI (from 1994 to December 2008), China Medical Academic Conference Database (from 1994 to December 2008) were electronically searched. We also searched the Meta-Register of Controlled Trials, Conference Proceedings of American Society of Hematology (from 1946 to December 2008) and Conference Proceedings of American Society |
| doi_str_mv | 10.3736/jcim20091102 |
| format | Article |
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To assess the efficacy and safety of ATO in combination with ATRA for APL.
The Cochrane Library (Issue 1, 2009), Cochrane Central Register of Controlled Trials (from 1970 to January 2009), MEDLINE (from 1978 to October 2008), EMBASE (from 1950 to March 2009), Chinese Biological Medical Literature Database (from 1978 to December 2008), CNKI (from 1994 to December 2008), China Medical Academic Conference Database (from 1994 to December 2008) were electronically searched. We also searched the Meta-Register of Controlled Trials, Conference Proceedings of American Society of Hematology (from 1946 to December 2008) and Conference Proceedings of American Society</description><identifier>ISSN: 1672-1977</identifier><identifier>DOI: 10.3736/jcim20091102</identifier><identifier>PMID: 19912733</identifier><language>chi</language><publisher>China</publisher><subject>Antineoplastic Combined Chemotherapy Protocols - therapeutic use ; Arsenicals - therapeutic use ; Humans ; Leukemia, Promyelocytic, Acute - drug therapy ; Oxides - therapeutic use ; Randomized Controlled Trials as Topic ; Survival Analysis ; Treatment Outcome ; Tretinoin - therapeutic use</subject><ispartof>Zhong xi yi jie he xue bao, 2009-11, Vol.7 (11), p.1024-1034</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19912733$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Xu, Shuang-nian</creatorcontrib><creatorcontrib>Chen, Jie-ping</creatorcontrib><creatorcontrib>Liu, Jian-ping</creatorcontrib><creatorcontrib>Xia, Yun</creatorcontrib><title>Arsenic trioxide in combination with all-trans retinoic acid for acute promyelocytic leukemia: a systematic review and meta-analysis</title><title>Zhong xi yi jie he xue bao</title><addtitle>Zhong Xi Yi Jie He Xue Bao</addtitle><description>The studies have demonstrated that arsenic trioxide (ATO) in combination with all-trans retinoic acid (ATRA) takes effects in treatment of acute promyelocytic leukemia (APL) through different underlying mechanisms. This has established the molecular foundation of ATO plus ATRA therapy. Currently, ATO plus ATRA has also been widely used in clinical practice.
To assess the efficacy and safety of ATO in combination with ATRA for APL.
The Cochrane Library (Issue 1, 2009), Cochrane Central Register of Controlled Trials (from 1970 to January 2009), MEDLINE (from 1978 to October 2008), EMBASE (from 1950 to March 2009), Chinese Biological Medical Literature Database (from 1978 to December 2008), CNKI (from 1994 to December 2008), China Medical Academic Conference Database (from 1994 to December 2008) were electronically searched. We also searched the Meta-Register of Controlled Trials, Conference Proceedings of American Society of Hematology (from 1946 to December 2008) and Conference Proceedings of American Society</description><subject>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</subject><subject>Arsenicals - therapeutic use</subject><subject>Humans</subject><subject>Leukemia, Promyelocytic, Acute - drug therapy</subject><subject>Oxides - therapeutic use</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Survival Analysis</subject><subject>Treatment Outcome</subject><subject>Tretinoin - therapeutic use</subject><issn>1672-1977</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kL1PwzAQxT2AaFW6MSNvTAF_JHHCVlV8SZVYYI4uzkUYYrvYDiU7fzhBwHB69979dDodIWecXUoly6tXbaxgrOaciSOy5KUSGa-VWpB1jKZlTIhSVLk8IQte11woKZfkaxMiOqNpCsZ_mg6pcVR72xoHyXhHDya9UBiGLAVwkQZMxvmZB2062vswN2NCug_eTjh4PaV5OOD4htbANQUap5jQwk8c8MPggYLrqMUEGTgYpmjiKTnuYYi4_tMVeb69edreZ7vHu4ftZpftuShSplrZC12hYnk-l6rKuut5LbCdbVEAr9uy0qzqCp3rKuc9a6Fgte4k8A56lCty8bt3vvZ9xJgaa6LGYQCHfoyNkjnPWVWWM3n-R46txa7ZB2MhTM3_4-Q32KlxiA</recordid><startdate>200911</startdate><enddate>200911</enddate><creator>Xu, Shuang-nian</creator><creator>Chen, Jie-ping</creator><creator>Liu, Jian-ping</creator><creator>Xia, Yun</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200911</creationdate><title>Arsenic trioxide in combination with all-trans retinoic acid for acute promyelocytic leukemia: a systematic review and meta-analysis</title><author>Xu, Shuang-nian ; Chen, Jie-ping ; Liu, Jian-ping ; Xia, Yun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p125t-7b3f2c8e70447047869df192eb47055a19b68c08d5c4c841f0ba509cd3a1dafe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2009</creationdate><topic>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</topic><topic>Arsenicals - therapeutic use</topic><topic>Humans</topic><topic>Leukemia, Promyelocytic, Acute - drug therapy</topic><topic>Oxides - therapeutic use</topic><topic>Randomized Controlled Trials as Topic</topic><topic>Survival Analysis</topic><topic>Treatment Outcome</topic><topic>Tretinoin - therapeutic use</topic><toplevel>online_resources</toplevel><creatorcontrib>Xu, Shuang-nian</creatorcontrib><creatorcontrib>Chen, Jie-ping</creatorcontrib><creatorcontrib>Liu, Jian-ping</creatorcontrib><creatorcontrib>Xia, Yun</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Zhong xi yi jie he xue bao</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Xu, Shuang-nian</au><au>Chen, Jie-ping</au><au>Liu, Jian-ping</au><au>Xia, Yun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Arsenic trioxide in combination with all-trans retinoic acid for acute promyelocytic leukemia: a systematic review and meta-analysis</atitle><jtitle>Zhong xi yi jie he xue bao</jtitle><addtitle>Zhong Xi Yi Jie He Xue Bao</addtitle><date>2009-11</date><risdate>2009</risdate><volume>7</volume><issue>11</issue><spage>1024</spage><epage>1034</epage><pages>1024-1034</pages><issn>1672-1977</issn><abstract>The studies have demonstrated that arsenic trioxide (ATO) in combination with all-trans retinoic acid (ATRA) takes effects in treatment of acute promyelocytic leukemia (APL) through different underlying mechanisms. This has established the molecular foundation of ATO plus ATRA therapy. Currently, ATO plus ATRA has also been widely used in clinical practice.
To assess the efficacy and safety of ATO in combination with ATRA for APL.
The Cochrane Library (Issue 1, 2009), Cochrane Central Register of Controlled Trials (from 1970 to January 2009), MEDLINE (from 1978 to October 2008), EMBASE (from 1950 to March 2009), Chinese Biological Medical Literature Database (from 1978 to December 2008), CNKI (from 1994 to December 2008), China Medical Academic Conference Database (from 1994 to December 2008) were electronically searched. We also searched the Meta-Register of Controlled Trials, Conference Proceedings of American Society of Hematology (from 1946 to December 2008) and Conference Proceedings of American Society</abstract><cop>China</cop><pmid>19912733</pmid><doi>10.3736/jcim20091102</doi><tpages>11</tpages></addata></record> |
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| identifier | ISSN: 1672-1977 |
| ispartof | Zhong xi yi jie he xue bao, 2009-11, Vol.7 (11), p.1024-1034 |
| issn | 1672-1977 |
| language | chi |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use Arsenicals - therapeutic use Humans Leukemia, Promyelocytic, Acute - drug therapy Oxides - therapeutic use Randomized Controlled Trials as Topic Survival Analysis Treatment Outcome Tretinoin - therapeutic use |
| title | Arsenic trioxide in combination with all-trans retinoic acid for acute promyelocytic leukemia: a systematic review and meta-analysis |
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